Urine-derived stem cell therapy shows promise for reducing surgery complications in boys with hypospadias

This study tested whether stem cell exosomes from a boy's own urine could improve healing after surgery for hypospadias, a common birth defect where the urethra opening is not at the tip of the penis. 82 boys with severe hypospadias were split into two groups: one received standard surgery plus the exosome treatment, the other had surgery alone. The goal was to see if the exosomes help rebuild the missing spongy tissue and lower the risk of complications like fistulas or narrowing.