Can a Blood-Derived patch reduce complications in penile surgery?

NCT ID NCT07757828

Not yet recruiting Disease control Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

First seen Aug 11, 2026 · Last updated Aug 12, 2026 · Updated 1 time

Summary

This trial tests whether applying a platelet-rich fibrin (PRF) membrane during hypospadias repair surgery improves healing and reduces complications like fistulas. PRF is made from the patient's own blood and is thought to support tissue repair. The study will include 80 boys with primary distal or mid-penile hypospadias undergoing standard repair. Half will receive the standard surgery plus PRF, and half will receive standard surgery alone, with outcomes compared.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Platelet-rich fibrin (PRF) applied during hypospadias repair surgery
What this could lead to: If effective, PRF could become a simple, safe addition to hypospadias surgery, reducing fistulas and improving healing.
What could go wrong: This is a small, early-stage trial. PRF may not significantly reduce complications, and results may not apply to all hypospadias cases.

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Conditions

The condition(s) this trial relates to.

hypospadias

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPOSPADIAS

Contacts and locations

Locations

Ain Shams University

Cairo, Abbasia, 11517, Egypt

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