Hypospadias
MONDO:0005345Hypospadias is the displacement of the urethral meatus on the ventrum of the penis. This abnormality is associated with a varyingly bent, twisted penis and opened dorsal prepuce.
Also known as: hypospadias, hypospadias (disease), hypospadias familial
30 clinical trials for this condition and its sub-types.
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Broader categories
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Could a blood clot improve penile surgery in boys?
Disease control Recruiting nowThis study compares two surgical techniques for correcting a common birth defect in boys where the urine opening is on the underside of the penis. One method uses a graft from tissue, while the other uses a special membrane made from the patient's own blood (platelet-rich fibrin)…
Phase: NA • Sponsor: National Children's Medical Center, Uzbekistan • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New pain block study aims to ease Kids' surgery recovery
Symptom relief Recruiting nowThis study compares two ways to block pain after hypospadias surgery in children aged 6 months to 7 years. One method uses a sacral erector spinae plane block, the other a caudal epidural block. Researchers will measure pain scores, how much extra pain medicine is needed, and any…
Phase: NA • Sponsor: TC Erciyes University • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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Writing away worry: study tests journaling for parents of kids with DSD
Symptom relief Recruiting nowThis study tests whether a guided journaling program can reduce anxiety in parents of children with urogenital conditions like differences of sex development (DSD) or hypospadias. Twenty parents will complete five writing prompts over several weeks and then share their experience…
Phase: NA • Sponsor: Sarah Schlegel • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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New study seeks best pain relief for young boys after surgery
Symptom relief Recruiting nowThis study compares two types of pain blocks—sacral erector spinae plane block and dorsal penile nerve block—in 70 boys aged 1-7 years having hypospadias surgery. The goal is to see which block provides better pain control after the operation. Researchers will measure pain scores…
Phase: NA • Sponsor: Medipol University • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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New pain block study aims to ease surgery recovery for toddlers
Symptom relief Recruiting nowThis study compares two types of nerve blocks—sacral erector spinae plane block and caudal block—to see which provides better pain relief after hypospadias repair in boys aged 1 to 5. Seventy children will receive one of the two blocks along with standard care. Researchers will m…
Phase: NA • Sponsor: Tanta University • Aim: Symptom relief
Last updated Jun 26, 2026 15:08 UTC
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Can a website ease Parents' worry about hypospadias surgery?
Knowledge-focused Recruiting nowThis study enrolls 324 parent-child pairs to see if a specially designed educational website helps parents feel more supported during hypospadias care. Parents are randomly assigned to either the study website or a basic information site. The goal is to learn how to improve commu…
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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Numbing injection may increase complication risk in Boys' genital surgery
Knowledge-focused Recruiting nowThis trial investigates whether a caudal nerve block, a common pain-relief method for children, increases the chance of a fistula (an abnormal opening) after surgery to correct hypospadias, a birth defect where the urine opening is on the underside of the penis. About 80 boys age…
Phase: NA • Sponsor: Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital • Aim: Knowledge-focused
Last updated Jul 02, 2026 00:00 UTC
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New app aims to track hypospadias complications over time
Knowledge-focused Recruiting nowThis study is testing a new web-based tool called the Worldwide Yearly Screening for Hypospadias (WYSH) Application. About 20 males who have had hypospadias repair surgery will use the app to answer questions about possible complications. The goal is to see if the app is easy to …
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Could everyday chemicals raise risk of birth defect? new study investigates
Knowledge-focused Recruiting nowThis study looks at whether exposure to certain chemicals (endocrine disruptors) during pregnancy increases the chance of a baby boy being born with hypospadias, a condition where the opening of the urethra is not at the tip of the penis. Researchers will compare 100 mothers of b…
Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC