HYPOGLYCEMIA

This is the first human study testing a new treatment called OPF-310, which involves transplanting specially encapsulated insulin-producing cells from pigs into people with unstable type 1 diabetes. The goal is to see if these transplanted cells can safely help control blood suga…

This study is testing whether a small, flexible tube (stent) placed during a camera procedure can effectively reverse a gastric bypass, offering a less invasive alternative to major surgery. It aims to help patients who are experiencing serious complications from their original w…

This study is testing whether a new wearable sensor can detect high or low blood sugar events by analyzing chemicals in a person's breath. Researchers are recruiting 30 teens with type 1 diabetes in Indianapolis to wear the sensor for 3 days and compare its readings to standard f…

This study aims to understand how gastric bypass surgery affects the body's insulin production and blood sugar control. Researchers are recruiting people who have had the surgery—some with and some without low blood sugar problems—as well as healthy people who haven't had surgery…

This National Institutes of Health study aims to better understand what causes dangerously low blood sugar levels during fasting. Researchers will evaluate 1,500 adults who experience low blood sugar when they haven't eaten for a while. Participants will undergo supervised fastin…

This is a small, early-stage study to test a new in-ear wearable device. The goal is to see if the device is comfortable and works well for measuring blood flow to the head. Researchers want to understand how blood flow changes in people who get low blood sugar after weight-loss …

This study aims to find out if sexual activity increases the risk of dangerously low blood sugar (hypoglycemia) in adults with type 1 or type 2 diabetes who use insulin. Researchers will remotely monitor 100 participants for 3 months using their continuous glucose monitors. Parti…

This study aims to understand how different levels of low blood sugar affect blood vessel function and heart health risks. Researchers will monitor 32 healthy volunteers while carefully lowering their blood sugar to specific levels. The goal is to gather basic knowledge about how…

This study aims to understand if a natural protein called C-peptide can help the liver make more sugar during episodes of low blood sugar (hypoglycemia). Researchers will compare people with type 1 diabetes to healthy volunteers to see if giving C-peptide during a controlled low …