HYPOGLYCEMIA

This early-phase study tests a new treatment called OPF-310, which uses pig islet cells enclosed in a protective capsule, for people with unstable type 1 diabetes who still experience dangerous low blood sugar episodes despite using an automated insulin pump and continuous glucos…

This study tests a new way to reverse gastric bypass surgery using a tube-like device called a stent placed through an endoscope. It is for people who have serious problems after bypass, like low blood sugar, blockages, or liver issues. The goal is to see if the stent can fix the…

This study aims to better understand why some people experience dangerously low blood sugar (hypoglycemia) and find better ways to diagnose and treat it. Up to 1,500 adults with confirmed low fasting blood sugar or insulin-secreting tumors will undergo supervised fasting and deta…

This study tests whether a wearable breath sensor can detect high or low blood sugar in teens with type 1 diabetes. Thirty participants aged 12-19 will wear the device for 72 hours and provide breath samples while checking their blood sugar. The goal is to find a painless, noninv…

This study looks at whether a special computer program that works with electronic medical records can help doctors better manage blood sugar levels in hospitalized adults. About 15,700 patients across several hospitals will be included. The goal is to see if the tool reduces high…

This early-stage study looks at how a protein called C-peptide might help the liver release sugar during low blood sugar (hypoglycemia) in people with type 1 diabetes. About 38 adults with type 1 diabetes will take part to see if C-peptide can boost glucagon, a hormone that raise…

This study looks at whether the standard A1C blood sugar test is accurate for people with type 2 diabetes who have a Left Ventricular Assist Device (LVAD). Researchers will compare A1C results with data from a continuous glucose monitor (CGM) worn for 3 months. The goal is to see…

This study looks at how gastric bypass surgery changes the way the body releases insulin. Researchers want to understand why some people develop dangerously low blood sugar years after surgery, while others see their diabetes improve. The study involves 160 participants, includin…

This study tests a tool called CGM ASSIST that uses a continuous glucose monitor and easy-to-read displays to help people with both dementia and diabetes, along with their caregivers and doctors, better understand blood sugar levels and make care decisions together. About 62 pati…

This study looks at whether sexual activity increases the risk of low blood sugar (hypoglycemia) in adults with type 1 or type 2 diabetes who use insulin and a continuous glucose monitor (CGM). One hundred participants will mark their sexual activity in a CGM app for 3 months, an…

This study looks at how different levels of low blood sugar (hypoglycemia) affect blood vessels in healthy adults. Researchers will measure changes in blood vessel function before and after controlled low blood sugar. The goal is to understand the body's response, not to treat a …

This small pilot study aims to see if a new in-ear wearable device can comfortably and reliably measure blood flow changes in the head during low blood sugar episodes. Researchers will compare people who have low blood sugar after bariatric surgery with those who don't. The goal …