HYPOGLYCEMIA

This study investigates whether drinking galactose before cycling can prevent low blood sugar (hypoglycemia) in people with type 1 diabetes. Fourteen participants will try four different drinks—dextrose, galactose, lactose, or a sweetened placebo—on separate days, then cycle for …

This study tested whether an enhanced continuous glucose monitor (eCGM) linked to a decision-support system can help older adults (65+) with type 1 diabetes manage their blood sugar. The system automatically uploads glucose, insulin, and activity data to give personalized insulin…

This study tested an artificial pancreas system that learns a person's exercise patterns to prevent low blood sugar (hypoglycemia) during and after moderate exercise. Fifteen adults with type 1 diabetes used the system for about 4 months, comparing it to a standard version. The g…

This study tested whether a real-time continuous glucose monitor could help detect and manage low blood sugar (hypoglycemia) in very low birth weight newborns. 48 infants were randomly assigned to either the continuous monitor or standard finger-stick testing for their first thre…

This pilot study tested whether high doses of omega-3 fatty acids (fish oil) and vitamin D are safe and can help preserve insulin production in people with type 1 diabetes. The trial included 27 participants, both children and adults, who had diabetes for up to 10 years. Research…

This completed study tested whether a continuous glucose monitor with predictive alerts (Dexcom G7) can reduce low blood sugar better than a standard alert monitor (Dexcom ONE+) in 11 adults with glycogen storage disease or congenital hyperinsulinism. Participants wore each devic…

This study looked at how the nervous system helps control blood sugar in people with type 1 diabetes who had islet cell transplants. Nine participants received drugs that block nerve signals or a placebo during controlled low blood sugar experiments. The goal was to learn whether…

This study looked at how blood sugar levels change in hospitalized babies with intestinal failure when their intravenous nutrition is given in cycles instead of continuously. Nine infants wore a small sensor on their thigh that measured glucose every 5 minutes for up to 30 days. …

This pilot study tested a new program to help prevent low blood sugar (hypoglycemia) in people with diabetes who take medications that can cause it. The program included a patient survey and a toolkit for doctors. The study involved 35 patients and their primary care providers at…

This study looks at whether using an automated insulin delivery system (a smart insulin pump and continuous glucose monitor) along with a low-carbohydrate diet can help restore the body's natural glucagon response to low blood sugar in people with type 1 diabetes. The glucagon re…

This study tested whether continuous glucose monitors (CGMs) can reliably track blood sugar levels in newborns at risk of low blood sugar (hypoglycemia) during their first 72 hours. Researchers enrolled 25 babies born large for gestational age or to mothers with diabetes. The goa…

This completed study at Brigham and Women's Hospital looked at how a moderately low blood sugar stress affects the brain and nervous system in 74 healthy adults. Participants underwent a procedure to lower blood sugar while brain scans measured changes in key brain regions. The g…

This study looked at how low blood sugar (hypoglycemia) affects the body's automatic nervous system, which controls heart rate and blood pressure. Researchers tested whether the drug spironolactone could block these effects in 28 healthy adults. Participants underwent controlled …

This study looked at how low blood sugar (hypoglycemia) affects the body's ability to control heart rate in people with well-controlled type 2 diabetes. Fourteen adults underwent two sessions of low blood sugar while their heart rate regulation was measured. The goal was to under…

This study looked at 62 people with type 1 diabetes to see if a test that measures the hormone glucagon can predict the risk of dangerously low blood sugar (hypoglycemia). Participants drank a special liquid meal or received an arginine injection to stimulate glucagon release, an…

This study looked at how often older adults with diabetes in long-term care facilities experience low blood sugar (hypoglycemia). Researchers used a continuous glucose monitor (CGM) worn for 10 days to track blood sugar levels in 86 participants. The goal was to better understand…

This study looked at whether continuous glucose monitors (CGMs) can help predict low blood sugar (hypoglycemia) in adults with type 2 diabetes. 41 participants wore either a regular CGM or a hidden one for a period of time. The goal was to compare how often low blood sugar occurr…