HYPERALGESIA
Clinical trials for HYPERALGESIA explained in plain language.
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New combo may stop opioids from making pain worse after surgery
Symptom relief CompletedThis study looked at whether giving ketamine during surgery and methadone after surgery can prevent a condition called opioid-induced hyperalgesia, where painkillers actually make you more sensitive to pain. 113 adults having open colorectal surgery took part. The goal was to see…
Matched conditions: HYPERALGESIA
Phase: NA • Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano • Aim: Symptom relief
Last updated May 17, 2026 08:49 UTC
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Laughing gas shows promise for pain control in small lab study
Knowledge-focused CompletedThis study tested whether breathing a mixture of 35% nitrous oxide (laughing gas) can reduce pain and skin sensitivity caused by mild electrical stimulation. Twenty healthy men took part in four sessions over nine weeks. The goal was to measure changes in pain area and monitor vi…
Matched conditions: HYPERALGESIA
Phase: PHASE1 • Sponsor: Air Liquide Santé International • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC