HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Clinical trials for HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA explained in plain language.
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New drug combo aims to wipe out HER2 low breast cancer before surgery
Disease control Recruiting nowThis study tests a drug called trastuzumab deruxtecan, which delivers chemotherapy directly to cancer cells with low levels of HER2, either alone or with anastrozole (a hormone blocker). The goal is to see if these treatments can eliminate all signs of cancer before surgery in pe…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated May 17, 2026 07:06 UTC
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New pill shows promise for Hard-to-Treat breast cancer in early trial
Disease control Recruiting nowThis early-phase study tests a new drug called BGB-43395, which blocks a protein (CDK4) that helps cancer cells grow. It is for people with advanced HR+/HER2- breast cancer or other solid tumors that have spread. The main goal is to find the safest and most effective dose, either…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: PHASE1 • Sponsor: BeOne Medicines • Aim: Disease control
Last updated May 17, 2026 06:50 UTC
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Immunotherapy boost may stop High-Risk breast cancer return
Disease control Recruiting nowThis large phase III trial tests whether adding the immunotherapy drug durvalumab to standard chemotherapy can prevent breast cancer from coming back in people with a high-risk form of hormone receptor-positive, HER2-negative breast cancer (called MammaPrint High 2 Risk). About 3…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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New hope for seniors: drug combo targets tough breast cancer
Disease control Recruiting nowThis study tests how well older adults (70+) with a certain type of advanced breast cancer tolerate a drug called abemaciclib combined with hormone therapy. Participants have already tried a similar drug that stopped working. The main goal is to track side effects and see if this…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 01, 2026 16:01 UTC
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New drug shows promise for Hard-to-Treat breast cancer in phase 2 trial
Disease control Recruiting nowThis study tests a drug called trastuzumab deruxtecan (T-DXd) against the usual treatment (a CDK4/6 inhibitor plus hormone therapy) for people with advanced breast cancer that is hormone receptor-positive and HER2-low or ultralow. The trial includes 200 adults whose cancer has a …
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: MedSIR • Aim: Disease control
Last updated Apr 30, 2026 15:51 UTC
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Smart bag and texts boost pill-taking in advanced breast cancer
Symptom relief Recruiting nowThis study tests whether a connected platform (a special medication bag called WiseBag plus text reminders) helps people with metastatic breast cancer take their CDK4/6 inhibitor pills more consistently. About 410 patients will either use the bag alone or the bag with text alerts…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: NA • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Symptom relief
Last updated May 17, 2026 06:51 UTC
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Acupuncture may help black women avoid debilitating joint pain during breast cancer treatment
Symptom relief Recruiting nowThis study tests whether in-person acupuncture or virtual acupressure can prevent joint pain caused by aromatase inhibitors, a common hormone therapy for breast cancer. It focuses on Non-Hispanic Black postmenopausal women with early-stage breast cancer, who are more likely to st…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: NA • Sponsor: Emory University • Aim: Symptom relief
Last updated May 17, 2026 06:51 UTC
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Can a vaginal moisturizer ease breast cancer side effects?
Symptom relief Recruiting nowThis study tests whether Revaree Plus, a vaginal moisturizer, can improve vaginal dryness in women with hormone-receptor-positive breast cancer. About 60 participants who have completed primary cancer therapy or are on maintenance treatment will use the product for 8 weeks. The g…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: PHASE4 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Symptom relief
Last updated May 12, 2026 13:39 UTC
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New study tracks sleep problems in breast cancer patients
Knowledge-focused Recruiting nowThis study follows 100 women with early-stage, hormone receptor-positive breast cancer to understand how their sleep changes during treatment. Researchers will use sleep watches and questionnaires to measure sleep quality and duration, and explore how stress, social support, and …
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 11, 2026 20:53 UTC