HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Clinical trials for HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA explained in plain language.
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New combo aims to outsmart resistant breast cancer
Disease control OngoingThis phase 2 trial tests whether adding the targeted drug alpelisib to ongoing hormone therapy can help people with a specific genetic mutation (PIK3CA) in advanced breast cancer that has stopped responding to hormone therapy alone. About 44 participants will take daily alpelisib…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: Marina N Sharifi • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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New antibody IMT-009 tested in patients with advanced cancers
Disease control OngoingThis early-phase trial tests a new antibody drug called IMT-009, given alone or with the cancer pill fruquintinib, in about 67 people with advanced solid tumors or lymphomas that have stopped responding to standard treatments. The main goals are to find a safe dose, understand si…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Immunitas Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Texting symptoms may keep young breast cancer patients on treatment
Symptom relief OngoingThis study tests whether regular symptom check-ins via text or email, plus educational materials, can help young women with early-stage breast cancer stay on their hormone therapy. Many women stop treatment early due to side effects. The trial involves 565 women and compares symp…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: NA • Sponsor: SWOG Cancer Research Network • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Texts and talks: a new way to boost breast cancer Pill-Taking
Symptom relief OngoingThis study tests whether text message reminders and phone counseling help women with early-stage breast cancer take their daily hormone therapy pills as prescribed. About 1,167 women will be split into groups: some get usual care, others get texts and/or motivational interviewing…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Symptom relief
Last updated Jun 26, 2026 15:07 UTC
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New scan could improve how we monitor bone metastases in breast cancer
Knowledge-focused OngoingThis phase 2 trial is testing whether a special type of PET/CT scan (FDG-PET/CT) can better measure how breast cancer that has spread to the bones responds to treatment. The study involves 138 participants with hormone receptor-positive metastatic breast cancer that is mostly in …
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Massive biobank aims to unlock Cancer's secrets
Knowledge-focused OngoingThis study collects tissue and blood samples from 1,600 people with various advanced cancers, along with their medical information, over the course of their treatment. Researchers will store these samples and data in a biobank for current and future studies. The goal is to better…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC