HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Clinical trials for HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA explained in plain language.
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New drug combo shows promise for Hard-to-Treat breast cancer
Disease control OngoingThis study tests a drug called alpelisib combined with standard hormone therapy for people with a specific type of advanced breast cancer (HR+, HER2-, with a PIK3CA mutation) whose cancer has worsened on hormone therapy alone. About 44 participants will take alpelisib daily along…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: Marina N Sharifi • Aim: Disease control
Last updated May 17, 2026 03:11 UTC
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New antibody drug shows promise in early cancer trial
Disease control OngoingThis early-stage study tests a new drug called IMT-009 in people with advanced solid tumors or lymphomas that have not responded to standard treatments. The main goals are to find a safe dose and learn about side effects. About 67 participants will receive the drug intravenously,…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Immunitas Therapeutics • Aim: Disease control
Last updated May 17, 2026 03:10 UTC
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New scan could improve monitoring of bone metastases in breast cancer
Diagnosis OngoingThis study looks at whether a type of PET/CT scan (FDG-PET/CT) can better measure how breast cancer that has spread to the bones responds to treatment. About 138 adults with hormone receptor-positive, HER2-known breast cancer that is mostly in the bones will get the scan before a…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Diagnosis
Last updated May 14, 2026 12:02 UTC
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Texts and talks: a new way to help breast cancer patients stay on track with meds
Symptom relief OngoingThis study tests whether adding text message reminders and/or telephone counseling helps breast cancer patients take their daily hormone therapy pills more consistently. About 1,167 women with early-stage hormone receptor-positive breast cancer will be followed for up to two year…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Symptom relief
Last updated May 17, 2026 03:17 UTC
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New study aims to keep young breast cancer patients on lifesaving pills
Symptom relief OngoingThis study tests whether regularly checking in on symptoms, along with providing educational materials, helps young women (ages 18-44) with early-stage hormone-positive breast cancer continue taking their hormone therapy as prescribed. Many women stop these pills early due to sid…
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Phase: NA • Sponsor: SWOG Cancer Research Network • Aim: Symptom relief
Last updated May 07, 2026 18:39 UTC
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Massive biobank aims to unlock Cancer's secrets
Knowledge-focused OngoingThis study collects tissue and blood samples, along with medical information, from 1,600 people with various advanced cancers. Researchers will store and study these samples over time to learn how cancer changes and why some treatments stop working. The goal is to improve future …
Matched conditions: HORMONE RECEPTOR-POSITIVE BREAST CARCINOMA
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated May 07, 2026 18:40 UTC