HEPATOBLASTOMA
Clinical trials for HEPATOBLASTOMA explained in plain language.
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Supercharged t cells take on hard-to-treat cancers in new trial
Disease control Recruiting nowThis early-phase study tests a new type of immunotherapy for adults with solid tumors that have a specific marker called GPC3. The treatment involves taking a patient's own T cells, adding genes to help them recognize and attack cancer cells, and then giving them back. The study …
Matched conditions: HEPATOBLASTOMA
Phase: PHASE1 • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated May 16, 2026 23:49 UTC
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Engineered immune cells take on childhood cancers in new trial
Disease control Recruiting nowThis early-stage trial tests a treatment where a child's own immune cells are collected, modified to better attack cancer, and given back as a one-time infusion. It is for children and young adults up to age 21 with solid tumors that have come back or not responded to standard th…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated May 16, 2026 23:48 UTC
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Promising new combo targets tough childhood liver cancer
Disease control Recruiting nowThis study tests a combination of three drugs (pucotenlimab, lenvatinib, and irinotecan) in children aged 2-18 with advanced hepatoblastoma that has not responded to prior treatment. The goal is to see if this combo can control the cancer longer. Participants will receive the tre…
Matched conditions: HEPATOBLASTOMA
Phase: NA • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated May 16, 2026 23:37 UTC
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New hope for rare cancers: immunotherapy trial targets tumors regardless of origin
Disease control Recruiting nowThis study tests the drug nivolumab in people with advanced rare cancers that have a specific marker (PD-L1). The goal is to see if the drug can shrink or control tumors for at least 12 months. About 28 adults who have not responded to standard treatments will take part.
Matched conditions: HEPATOBLASTOMA
Phase: PHASE2 • Sponsor: Instituto do Cancer do Estado de São Paulo • Aim: Disease control
Last updated May 16, 2026 23:37 UTC
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New hope for kids with relapsed cancers: experimental combo enters human testing
Disease control Recruiting nowThis early-phase study tests a four-drug combination (vorinostat, vincristine, irinotecan, and temozolomide) in children, teens, and young adults up to age 30 whose solid tumors or brain cancers have returned or not responded to standard treatment. The main goals are to find a sa…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE1 • Sponsor: New York Medical College • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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New CAR t therapy targets Hard-to-Treat childhood cancers
Disease control Recruiting nowThis early-stage trial tests a new type of immunotherapy for children and young adults with certain solid tumors that have come back or not responded to treatment. The therapy uses the patient's own immune cells, which are modified in a lab to better recognize and attack cancer c…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE1 • Sponsor: Seattle Children's Hospital • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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New hope for kids with rare liver cancer: smarter chemo aims to boost survival
Disease control Recruiting nowThis study is testing a new combination of chemotherapy drugs for children and teens with hepatoblastoma, a rare liver cancer. The goal is to improve survival, especially for high-risk patients who currently have only a 40% chance of living 3 years. The study will enroll 100 part…
Matched conditions: HEPATOBLASTOMA
Phase: PHASE2 • Sponsor: Sun Yat-sen University • Aim: Disease control
Last updated May 12, 2026 13:39 UTC
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Scientists dive into DNA of Kids' liver tumors to unlock secrets
Knowledge-focused Recruiting nowThis study aims to uncover the genetic and molecular causes of liver cancer in children. Researchers will analyze DNA, gene activity, and other markers from up to 1,600 participants, including children with liver tumors and their biological relatives. The goal is to better classi…
Matched conditions: HEPATOBLASTOMA
Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC