New hope for kids with relapsed cancers: experimental combo enters human testing

NCT ID NCT04308330

First seen Apr 23, 2026 · Last updated May 14, 2026 · Updated 5 times

Summary

This early-phase study tests a four-drug combination (vorinostat, vincristine, irinotecan, and temozolomide) in children, teens, and young adults up to age 30 whose solid tumors or brain cancers have returned or not responded to standard treatment. The main goals are to find a safe dose and understand side effects. About 30 participants will be enrolled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • New York Medical College

    RECRUITING

    Valhalla, New York, 10595, United States

    Contact

    Contact

Conditions

Explore the condition pages connected to this study.