Supercharged immune cells take on Hard-to-Treat cancers

NCT ID NCT06198296

First seen Nov 03, 2025 · Last updated Jun 12, 2026 · Updated 35 times

Summary

This early-phase trial tests a new type of immunotherapy for adults with solid tumors that have a specific marker called GPC3. Researchers take a patient's own T cells and add three new genes to help them recognize and attack cancer cells more effectively, plus a safety switch to stop them if needed. The study aims to find the safest dose and see if the treatment can shrink tumors. About 21 participants with cancers like liver cancer or Wilms tumor will be enrolled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Houston Methodist Hospital

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.