HEART DISEASES

This study tests whether a civic engagement program can help rural adults improve their heart health. About 2,400 participants will work together to identify and overcome local barriers to healthy eating and physical activity. The goal is to see if this community-driven approach …

This study tests whether using an insertable heart monitor to guide early treatment can reduce the amount of time people spend in atrial fibrillation (AFib) after a catheter ablation. About 120 adults with AFib will get a small monitor placed under their skin before or during the…

This study tests a new device called the PULSTA valve, which is placed inside the heart's pulmonary artery using a thin tube through a blood vessel, avoiding open-heart surgery. It is for people whose pulmonary valve is leaky or narrowed, often due to a birth defect. The study wi…

This study looks at whether giving doctors a special risk score—which combines a person's genes with things like cholesterol and age—helps them make better decisions to prevent heart disease. About 1000 people at risk for heart disease but who have never had a heart attack will t…

This study watches how over 800 heart failure patients in Germany use the drug dapagliflozin in everyday life. Researchers track treatment changes, symptoms, and quality of life to see how well the drug works outside of controlled trials. No new treatments are tested—just real-wo…

This study looks at whether changing how people connect online can help improve attitudes toward COVID-19 vaccines and related health behaviors. About 4,500 adults in the US with internet access are taking part. Researchers are testing if reducing online segregation and increasin…

This study tests whether a phone app called StudyU can help older adults with a type of heart failure (HFrEF) reach the recommended dose of their beta blocker medicine. Five participants will use the app and complete surveys about how easy and useful it is. The goal is to see if …

This study was designed to see if cholesterol-lowering PCSK9 inhibitors also reduce inflammation in the arteries of people with heart disease. Researchers planned to use a special imaging scan to measure inflammation in the aorta. The study was withdrawn before enrolling any part…