HEALTHY ADULT PARTICIPANTS

This study compared a traditional scalpel to three different dental lasers for a common gum surgery called vestibuloplasty. The surgery was performed on 36 healthy, toothless patients to prepare their gums for dentures. Researchers found that the laser-treated sides had significa…

This small pilot study looked at whether eating apples changes the chemical byproducts produced by gut bacteria. Fifteen healthy adults ate three apples daily for three days while otherwise keeping their normal diet. Researchers analyzed stool samples before and after to see if a…

This study aimed to understand how a new cancer drug candidate, vorasidenib, might change how the body processes several other common medications. It involved 28 healthy adult participants who took the other drugs alone and then together with vorasidenib. The goal was to gather s…

This study aimed to see if taking two lower-strength pills of the drug centanafadine is equivalent to taking one higher-strength pill. It involved 44 healthy adult volunteers who took the drug in different forms. The main goal was to compare how the body absorbs and processes the…

This study aimed to understand how a new Pfizer drug candidate, PF-07248144, is absorbed and processed by the body. Eight healthy adult volunteers received the drug both by mouth and by IV, with a tiny, safe radioactive marker to help track it. Researchers collected blood, urine,…

This early-stage study aimed to check if a new compound called TBD09 is safe for people and to see how the body processes it. It involved 36 healthy adults who took either TBD09 or a placebo pill daily for 84 days. Researchers closely monitored participants for any side effects a…

This study aimed to see if wearing minimalist shoes (thin, flexible, flat shoes) for everyday activities over a year changes foot health compared to regular shoes. Researchers measured foot muscle size and strength, balance, and foot sensitivity in 90 healthy adults. One group wo…