HEAD AND NECK SQUAMOUS CELL CARCINOMA
Clinical trials for HEAD AND NECK SQUAMOUS CELL CARCINOMA explained in plain language.
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New drug duo aims to shrink head and neck tumors before surgery
Disease control Not yet recruitingThis study tests whether giving a new drug (becotatug vedotin) alone or with immunotherapy before surgery can improve outcomes for people with advanced head and neck cancer. About 120 adults with resectable tumors will receive the treatment before their operation. The main goal i…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: West China Hospital • Aim: Disease control
Last updated Jun 16, 2026 12:51 UTC
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Experimental combo aims to boost immune attack on head and neck tumors
Disease control Not yet recruitingThis early-stage study tests a combination of two drugs—decitabine (a chemotherapy that can reactivate genes) and nivolumab (an immunotherapy that helps the immune system fight cancer)—in people with advanced head and neck cancer that has come back or spread. About 15 participant…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: Kyunghee Burkitt, DO, PhD • Aim: Disease control
Last updated Jun 15, 2026 19:03 UTC
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New combo therapy aims to boost survival in head and neck cancer patients
Disease control Not yet recruitingThis study tests whether adding the immunotherapy drug camrelizumab to either an EGFR antibody or chemotherapy helps people with advanced head and neck cancer live longer. About 246 adults with stage III or IV head and neck cancer will receive the treatment before and after surge…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE3 • Sponsor: Yue He, MD • Aim: Disease control
Last updated Jun 15, 2026 18:56 UTC
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New combo therapy aims to keep head and neck cancer at bay
Disease control Not yet recruitingThis study tests whether adding the drug benmelstobart to standard post-surgery radiation and nimotuzumab can help prevent head and neck cancer from coming back. About 386 adults with intermediate-risk features after surgery will take part. The main goal is to see if the new comb…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2, PHASE3 • Sponsor: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University • Aim: Disease control
Last updated Jun 10, 2026 13:27 UTC
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New drug QLS5316 enters first human tests for advanced cancers
Disease control Not yet recruitingThis early-phase study tests a new drug called QLS5316 in about 300 adults with advanced solid tumors (such as colorectal, stomach, head and neck, or lung cancer) that have not responded to standard treatments. The main goals are to check the drug's safety, find the right dose, a…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: Qilu Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 10, 2026 13:26 UTC
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Virus and chemo combo takes on hard-to-treat head and neck cancer
Disease control Not yet recruitingThis study tests a combination of a modified virus (H101) and a targeted chemotherapy procedure (TACE) in 20 adults with head and neck cancer that has returned or spread after at least two standard treatments. The goal is to shrink tumors and boost the immune system while limitin…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: West China Hospital • Aim: Disease control
Last updated Jun 09, 2026 12:08 UTC
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Shorter radiation course could ease recovery for head and neck cancer patients
Disease control Not yet recruitingThis study tests a shorter, more intense radiation schedule (hypofractionated radiotherapy) in 60 adults with intermediate-risk head and neck cancer who have had surgery. The goal is to see if this approach is safe and effective at controlling the cancer while reducing long-term …
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated Jun 01, 2026 17:58 UTC
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Radiation plus immunotherapy shows promise in head and neck cancer trial
Disease control Not yet recruitingThis study tests whether adding radiation to immunotherapy before surgery can improve outcomes for people with advanced head and neck cancer. About 36 adults with stage III-IVB disease will be randomly assigned to receive either the combination or immunotherapy alone before their…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Chen Chunyan • Aim: Disease control
Last updated Jun 01, 2026 17:55 UTC
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New radioactive antibody lights up hard-to-treat cancers in early trial
Diagnosis Not yet recruitingThis early-phase study tests a new radioactive antibody (NTH-2403) that targets a protein found on certain cancer cells. The goal is to see if it is safe and can help doctors see tumors more clearly using imaging. About 16 adults with advanced colorectal, head and neck, lung, or …
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: Radiopharm Theranostics, Ltd • Aim: Diagnosis
Last updated Jun 15, 2026 18:55 UTC
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Glow-in-the-dark dye could help surgeons spot cancer during head and neck surgery
Diagnosis Not yet recruitingThis early-phase trial tests a fluorescent dye called ABY-029 that may help surgeons see head and neck cancer tumors more clearly during surgery. About 24 adults with head and neck squamous cell carcinoma will receive a tiny amount of the dye before their operation. Researchers w…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: Dartmouth-Hitchcock Medical Center • Aim: Diagnosis
Last updated Jun 11, 2026 12:10 UTC
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Blood test could spot hidden throat cancers before symptoms start
Diagnosis Not yet recruitingThis study aims to see if a simple blood test can find HPV-related oropharyngeal cancer early in men aged 50 and older who have no symptoms. Researchers will check blood for two markers of HPV and then follow up with those who test positive to find and treat any tumors. If succes…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: UNICANCER • Aim: Diagnosis
Last updated Jun 10, 2026 13:29 UTC
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Could less radiation be just as effective for HPV throat cancer?
Symptom relief Not yet recruitingThis study is for people with HPV-related oropharyngeal (throat) cancer, which often responds well to treatment. The goal is to see if lowering the radiation dose to certain areas can reduce side effects like dry mouth without hurting the chance of curing the cancer. About 132 pa…
Matched conditions: HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: University of Maryland, Baltimore • Aim: Symptom relief
Last updated Jun 08, 2026 13:07 UTC