GRAFT -VERSUS-HOST-DISEASE

This study tested whether the drug pomalidomide could help control chronic graft-versus-host disease (GvHD) in people who didn't respond to standard steroid treatments. GvHD is a serious complication that can occur after a stem cell transplant, where the donor's immune cells atta…

This study tested whether the drug nilotinib could help control chronic graft-versus-host disease in patients who had already tried and failed treatment with imatinib. The trial involved 65 adults who had received stem cell transplants and developed this serious complication wher…

This study tested whether Prochymal, a stem cell therapy, could help patients with severe graft-versus-host disease (GVHD) that hadn't responded to standard treatments. GVHD is a dangerous complication that can occur after a bone marrow transplant, where the donor cells attack th…

This study tested whether a lower dose of a drug called cyclophosphamide could effectively prevent a serious complication called graft-versus-host disease (GVHD) after a stem cell transplant. The trial involved 35 adults with blood cancers or disorders who received a transplant f…

This study tested a new type of PET scan to see if it could find and predict Graft Versus Host Disease (GVHD), a serious complication after a bone marrow or stem cell transplant. Researchers gave the scan to patients who were suspected of having GVHD or were at high risk for it, …

This study tested if adding a new drug called BMS-986004 to standard anti-rejection medicine could safely prevent a serious complication called acute Graft-Versus-Host Disease (GVHD). It involved 45 patients with blood cancers who received a stem cell transplant from a donor. The…

This study tested if a special light-based blood treatment could prevent a serious complication called graft-versus-host disease (GVHD) in patients receiving a stem cell transplant for blood cancer. Researchers compared this treatment, which has milder side effects, to standard p…