New hope for GVHD patients who failed first drug
NCT ID NCT02891395
First seen Jan 06, 2026 · Last updated May 14, 2026 · Updated 26 times
Summary
This study tested a drug called nilotinib in 65 adults with chronic graft-versus-host disease (GVHD), a complication after a stem cell transplant where donor cells attack the patient's body. Participants had already tried imatinib without success. The goal was to see if nilotinib could control the disease by measuring response after 3 months. The study was completed and aimed to offer a treatment option for those who did not respond to standard therapy.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHU Besançon
Besançon, France
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CHU Bordeaux
Bordeaux, France
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CHU Clémenceau
Caen, France
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CHU Grenoble
Grenoble, France
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CHU Hotel Dieu
Nantes, France
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CHU Purpan
Toulouse, France
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CHU Sart Tilman
Liège, Belgium
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CHU d'Amiens
Amiens, France
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CHU d'Angers
Angers, France
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CHU de Clermont Ferrand
Clermont-Ferrand, France
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CHU de Lyon
Lyon, France
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CHU de Nice
Nice, France
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CHU de STRASBOURG
Strasbourg, France
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Centre Henri Becquerel
Rouen, France
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Centre hospitalier et régional de Lille
Lille, France
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Diseases of Blood Service HURIEZ hospital CHRU de LILLE
Lille, 59037, France
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HIA de Percy
Clamart, France
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Hopital Morvan
Brest, France
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Hopital NECKER
Paris, France
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Hôpital Saint Eloi
Montpellier, France
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Hôpital pitié Salpetrière
Paris, France
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Institut Paoli Calmettes
Marseille, France
Conditions
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