New imaging tracer may help detect dangerous transplant complication

NCT ID NCT03367962

First seen Dec 12, 2025 · Last updated May 07, 2026 · Updated 20 times

Summary

This early-phase study tested a new imaging tracer called [18F]F-AraG in 9 patients who had or were at high risk for graft-versus-host disease (GVHD) after a stem cell transplant. The tracer is designed to highlight activated T cells, which cause GVHD. Researchers compared the PET scan results with biopsies to see if the tracer could accurately identify GVHD sites. The study was completed but did not include healthy volunteers as originally planned.

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Contacts and locations

Locations

  • Stanford Hospital

    Stanford, California, 94305, United States

Conditions

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