New hope for tough GvHD: pomalidomide shows promise in small trial

NCT ID NCT01688466

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested a drug called pomalidomide in 34 adults with chronic graft-versus-host disease (GvHD) that didn't improve with standard treatments. GvHD can happen after a stem cell transplant when the donor cells attack the recipient's body. Participants took pomalidomide capsules daily for up to 6 months, and researchers checked if the disease got better or worse. The goal was to see if the drug is safe and can help control this condition.

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Conditions

The condition(s) this trial relates to.

chronic graft versus host disease graft versus host disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center, 9000 Rockville Pike

    Bethesda, Maryland, 20892, United States