New hope for stem cell transplant patients: drug targets stubborn GvHD

NCT ID NCT01688466

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 28 times

Summary

This study tested a drug called pomalidomide in 34 adults with chronic graft-versus-host disease (GvHD), a condition where donor immune cells attack the recipient's body after a stem cell transplant. Participants had GvHD that did not improve with standard treatments. They took pomalidomide capsules daily for up to 6 months, with possible extension. The goal was to see if the drug could safely control the disease and reduce symptoms.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center, 9000 Rockville Pike

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.