GLAUCOMA

This study tests whether a combination eye drop (netarsudil/latanoprost) can improve vision and reduce corneal thickness in people with glaucoma and a condition called pseudophakic bullous keratopathy, where the cornea swells after cataract surgery. Half of the 50 participants re…

This study compared two small eye implants, Hydrus and iStent, placed during cataract surgery to help lower eye pressure in people with open-angle glaucoma. 65 patients were followed long-term to see which device worked better and was safer. The goal was to reduce the need for gl…

This study compared two types of glaucoma surgery—standard trabeculectomy and a smaller 'micro' version—to see which one lowers eye pressure better and causes fewer complications. Researchers followed 100 patients for 3 months after surgery. The goal is to find out if the smaller…

This study compared two types of tube shunts (Baerveldt 350 and Ahmed ClearPath 250) in 80 adults with glaucoma that was not controlled by other treatments. The goal was to see which device lowers eye pressure better and is safer. Both implants are used to drain fluid and protect…

This study tested a new eye drop called QLS-111 in 37 people with normal tension glaucoma, a type of glaucoma where eye pressure is not high but vision still gets damaged. The goal was to see if QLS-111 is safe and can lower eye pressure better than a standard drop called timolol…

This study tested a new, less invasive surgery called MIMS for people with glaucoma. The goal was to see if it lowers eye pressure as well as traditional surgery but with fewer side effects. 23 adults with glaucoma took part. The results will help doctors understand if MIMS is a …

This study looked at 70 people with mild to moderate glaucoma or high eye pressure. All received a laser treatment called selective laser trabeculoplasty (SLT). Afterward, half used Rocklatan eye drops and half used artificial tears. The goal was to see if Rocklatan lowered eye p…

This study from the Mayo Clinic tested a laser procedure called MP-TSCPC in 65 glaucoma patients to see how well it lowers eye pressure. Researchers tracked patients for one year after the procedure, measuring changes in eye pressure, medication use, and vision. The goal was to e…

This study tested a small implant called XEN in 150 people whose glaucoma was still out of control despite previous surgeries. The implant was placed in the eye to help drain fluid and lower pressure. Researchers tracked eye pressure, vision changes, and how many medications pati…

This completed Phase 2 trial tested two strengths of a new eye drop called T4090 against the existing drug Rhopressa in 161 adults with open-angle glaucoma or ocular hypertension. The goal was to see which better lowers eye pressure over 7 weeks. Participants used one drop daily …

This study tested whether a daily oral solution containing citicoline and nicotinamide (Kron) could improve eye function in 30 people with open-angle glaucoma. Participants took the supplement and had their retinal and visual cortex activity measured. The goal was to see if the c…

This study tested a gel called MINIVISC® PLUS, used during eye surgeries like cataract removal and glaucoma surgery to protect delicate tissues and keep the eye stable. Researchers checked if the gel was safe and worked well in 134 patients. The main focus was on eye pressure aft…

This study tested a device that combines a bimatoprost implant with a special intraocular lens to treat both cataracts and glaucoma or high eye pressure. Twenty-four participants received the implant during cataract surgery. The main goals were to see if it lowers eye pressure an…

This study tests whether a smartphone-based camera can accurately screen for eye diseases such as diabetic retinopathy, glaucoma, and age-related macular degeneration. About 550 patients will have photos taken with both the smartphone camera and standard equipment. Ophthalmologis…

This study tested an AI tool called VeriSee GLC that analyzes color images of the back of the eye to find signs of glaucoma. Researchers looked at 773 adults' existing eye images to see how well the AI could identify people who might have glaucoma, comparing its results to a pane…

This study tested whether an AI tool can help eye doctors diagnose four common retinal diseases (diabetic retinopathy, age-related macular degeneration, retinal vein occlusion, and glaucoma) more accurately and quickly. Ten doctors from five hospitals read fundus images both with…

This study tested whether a high-resolution eye scan called SD-OCT can diagnose glaucoma more accurately than standard methods. Researchers compared 109 people with and without glaucoma using the scan. The goal was to see if this technology could catch the disease earlier, before…

This study compared three different devices that measure side vision in people with glaucoma. Fifty-four adults each took all three tests in one visit. Researchers timed how long each test took and checked how well the results matched. The goal is to find which test is fastest an…

This study tested a new smart contact lens called miLens that records eye pressure patterns over 24 hours in 86 adults with glaucoma and healthy volunteers. Participants wore the lens in one eye and took smartphone readings every 15 minutes while awake. Researchers compared the l…

This study tested a new imaging device called the P200TE on 53 people with glaucoma. The goal was simply to see how well it could capture images of the back of the eye. It was not a treatment study, so there were no health benefits or risks for participants.

This study tested how well two different eye imaging machines (Topcon Maestro2 and Zeiss Cirrus 5000) agree when measuring retinal thickness in people with glaucoma. Researchers scanned 141 eyes from patients with mild to severe glaucoma using both devices. The goal was to see if…

This study tested four new types of tonometer tips that can measure eye pressure without numbing drops. 49 adults getting routine eye exams tried the new tips and rated them for comfort. The goal is to find the best design for a home-use device that makes glaucoma monitoring easi…

This study looked at whether a supplement called citicoline can improve vision in people with glaucoma after they have eye surgery. Six adults took either citicoline or a placebo for a short time. The goal was to see if citicoline could help protect the optic nerve and improve vi…

This study looked at whether playing music helps children with glaucoma stay focused during a visual field exam (a test that checks side vision). 38 children took part, and researchers measured how often they made mistakes or lost focus. The goal was to see if music could make th…

This study tested a six-month personalized coaching program for glaucoma patients who struggle to use their eye drops regularly. 236 participants received either coaching or standard care. The program used motivational interviewing and tailored education to help patients overcome…

This trial tests a new device called P200TxE that takes detailed images of the back of the eye. Researchers want to see how well it captures images in people with retinal diseases like glaucoma or macular degeneration. The study involves adults aged 22 and older who have been dia…

This study used MRI to measure blood flow in the eye's main artery in 20 adults with untreated glaucoma and compared it to healthy people. The goal was to understand how blood flow problems might contribute to glaucoma damage. Participants had one MRI scan, and no treatment was g…

This study used high-powered 3-Tesla MRI to compare the visual pathways in the brains of 114 people with glaucoma and healthy volunteers. Researchers looked at the structure and volume of brain areas involved in vision to see if glaucoma causes damage beyond the eye. The goal was…

This study looked at how eye pressure changes when breath-hold divers hold their breath. Forty divers had their eye pressure, oxygen levels, heart rate, and blood pressure measured before, during, and after holding their breath. The goal was to understand these changes and how th…

This study followed 326 people newly diagnosed with glaucoma or high eye pressure to see how many got worse over 2 to 4 years of standard monitoring in hospital eye clinics. Researchers measured the rate of disease progression and looked for factors that might predict worsening. …

This study tested four different approaches to find and treat eye diseases like cataracts, glaucoma, and diabetic retinopathy in communities in Nepal. Over 87,000 people aged 50 and older took part. The goal was to see which method—comprehensive screening, cataract camps, communi…

This study looked at how the eye produces and drains fluid to understand why glaucoma medications lower eye pressure more in some people than others. Researchers measured eye fluid production, drainage, and pressure in 59 adults with glaucoma or high eye pressure before and after…

This small, completed study looked at how many Hydrus microstent surgeries glaucoma fellows need to perform before they become skilled. Researchers graded videos of surgeries from 5 fellows at three eye centers. The goal was to find the average number of cases needed to reach an …

This study looked at whether a central monitoring station outside the operating room could safely replace having an anesthesia nurse in each room during eye surgeries like cataract removal. Researchers compared the rate of complications (like high blood pressure or low oxygen) be…

This study looked at 120 children with glaucoma or suspected glaucoma who needed eye exams under anesthesia. The goal was to see if a standard anesthesia plan could produce consistent and reliable eye pressure measurements. Researchers measured how deep the anesthesia was and com…

This study tested whether a simple app, available in English, Spanish, and Cantonese, could help glaucoma patients better remember their multiple eye drop schedules. Twenty participants either used the app or received standard instructions. After one month, researchers compared h…

This study looked at 60 people with glaucoma to see how changes in the eye's structure relate to vision loss. Researchers used eye scans (OCT) and vision field tests to measure nerve thickness, blood vessel density, and light sensitivity. The goal was to better understand the lin…

This study surveyed 379 eye clinic patients in Pakistan to find out how much they know about glaucoma, a disease that can cause blindness without early treatment. Participants answered a questionnaire about their eye history, knowledge of glaucoma, and beliefs about its curabilit…