GIANT CELL ARTERITIS

This study is testing whether a weekly injection called abatacept can help control giant cell arteritis, a serious condition that causes inflamed blood vessels in the head. The trial will involve 78 adults with recently active disease, comparing the drug to a placebo injection fo…

This study aims to see if lower-quality MRI scans can still accurately diagnose giant cell arteritis, a serious inflammatory condition affecting arteries in the head. Researchers will compare different MRI scan resolutions in 133 adults suspected of having the disease. The goal i…

This study is testing whether giving patients with polymyalgia rheumatica (PMR) or giant cell arteritis (GCA) an extra dose of the hormone hydrocortisone during stressful times can improve their quality of life, especially by reducing severe fatigue. The trial includes 250 adults…

This study is creating a large collection of health information and biological samples from people with various rheumatic diseases like rheumatoid arthritis and lupus. The goal is to help researchers better understand what causes these conditions and how they progress over time. …

This study aims to find out if specific signs seen on ultrasound scans of the temples and armpits can predict when symptoms of giant cell arteritis will return. Researchers will follow 100 patients with this condition during their regular doctor visits, using standard ultrasound …

This study aims to collect and store existing tissue samples from people already enrolled in other vasculitis research studies. Researchers will analyze these samples along with health data to better understand what causes these rare inflammatory diseases. The goal is to generate…

This study aims to better understand the long-term risks for people with giant cell arteritis and polymyalgia rheumatica, particularly focusing on heart complications and side effects from steroid medications. Researchers will follow 400 adult patients for 5-10 years, using imagi…

This study is testing whether MRI scans can help doctors see inflammation in the arteries that supply blood to the head, brain, and eyes in people suspected of having giant cell arteritis. It involves 400 adults aged 50+ who are showing new symptoms. Participants will have MRI sc…

This study aims to learn more about a group of rare diseases called vasculitis, which cause damaging inflammation in blood vessels. Researchers will follow up to 4,000 people, including patients and healthy volunteers, over many years to track symptoms, collect blood and tissue s…

This study aims to find genes that increase the risk of developing vasculitis, a group of rare and severe diseases that cause inflammation of blood vessels. Researchers will collect DNA and health information from 1,000 people diagnosed with one of six specific types of vasculiti…