GIANT CELL ARTERITIS

This study tests whether the drug abatacept can help people with giant cell arteritis, a condition that causes inflammation in blood vessels. About 78 adults with newly diagnosed or relapsing disease will receive either abatacept or a placebo for up to 12 months. The goal is to s…

This study tests whether lower-resolution MRI scans can still accurately detect giant cell arteritis, a serious inflammation of the arteries that can cause blindness or stroke if not treated quickly. Researchers will compare different MRI techniques in 133 adults suspected of hav…

This study looks at whether taking extra hydrocortisone during times of stress (like illness or emotional strain) can improve fatigue and daily well-being in people whose adrenal glands are underactive due to long-term prednisolone treatment for polymyalgia rheumatica or giant ce…

This study collects tissue samples from 1,000 people with various forms of vasculitis (blood vessel inflammation). Researchers will analyze the samples along with medical data to find genes linked to the disease and spark new ideas for diagnosis and treatment. Participants must a…

This study is building a large database and sample bank from 5,000 adults with various rheumatic diseases like rheumatoid arthritis, lupus, and psoriatic arthritis. Researchers will use this information to find links between patient outcomes and biological markers. The goal is to…

This study tests whether MRI scans can spot inflammation in the arteries of the head, brain, and eyes in people with suspected giant cell arteritis (GCA). Researchers will enroll 400 adults aged 50 and older who have new or worsening symptoms and high inflammation levels. The goa…

This study follows 400 adults diagnosed with giant cell arteritis or polymyalgia rheumatica to track serious long-term complications. Researchers will monitor for new or worsening aortic aneurysms, aortic dissection, and side effects from steroid treatment. The goal is to better …

This study collects DNA samples and health information from 1,000 people with vasculitis—a group of rare diseases where blood vessels become inflamed. Researchers hope to identify genes that increase the risk of developing these conditions, which could lead to better tests and tr…

This study looks at whether ultrasound images of the temporal and axillary arteries can help predict when giant cell arteritis (GCA) will flare up again. Researchers will follow 100 adults with GCA to see if certain ultrasound patterns are linked to relapses. The goal is to impro…

This study is following up to 4,000 people with vasculitis (a group of diseases that cause blood vessel inflammation) and healthy volunteers to learn more about the disease. Researchers will collect blood, urine, imaging, and genetic samples over time to find better ways to diagn…