Scientists build tissue bank to unlock vasculitis mysteries

NCT ID NCT02967068

Recruiting now Knowledge-focused Sponsor: University of Pennsylvania Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study collects tissue samples from 1,000 people with various forms of vasculitis, a group of rare inflammatory blood vessel diseases. Researchers will analyze the samples alongside clinical data to identify genes that increase risk and to spark new ideas for diagnosis and treatment. The goal is to better understand what causes these diseases.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could uncover genetic causes of vasculitis and lead to new diagnostic tests or therapies.
What could go wrong: This is an observational tissue collection study, not a treatment trial. It may not directly lead to new treatments, and results may take years.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

aortitis cutaneous vasculitis eosinophilic granulomatosis with polyangiitis Giant Cell Arteritis granulomatosis with polyangiitis immunoglobulin A vasculitis microscopic polyangiitis polyarteritis nodosa skin vascular disease Takayasu arteritis temporal arteritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AORTITIS CHURG-STRAUSS SYNDROME CUTANEOUS VASCULITIS EOSINOPHILIC GRANULOMATOSIS WITH POLYANGIITIS GIANT CELL ARTERITIS GRANULOMATOSIS WITH POLYANGIITIS (WEGENER'S) HENOCH-SCHONLEIN PURPURA IGA VASCULITIS MICROSCOPIC POLYANGIITIS POLYARTERITIS NODOSA TAKAYASU ARTERITIS

Contacts and locations

Locations

Boston University School of Medicine
COMPLETED

Boston, Massachusetts, 02118, United States
Brigham and Women's Hospital
COMPLETED

Boston, Massachusetts, 02115, United States
Cleveland Clinic
COMPLETED

Cleveland, Ohio, 44195, United States
St. Joseph's Healthcare
RECRUITING

Hamilton, Ontario, L8N 3B6, Canada
University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
University of Pittsburgh
COMPLETED

Pittsburgh, Pennsylvania, 15261, United States
University of Toronto Mount Sinai Hospital
RECRUITING

Toronto, Ontario, M5G 1X5, Canada
University of Utah
COMPLETED

Salt Lake City, Utah, 84132, United States

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