PET scans could revolutionize monitoring of rare inflammatory disease

NCT ID NCT07712172

First seen Jul 17, 2026 ยท Last updated Jul 17, 2026

Summary

This study explores whether a special type of PET/CT scan, using a radioactive tracer called 18F-FDG, can accurately measure disease activity in people with granulomatosis with polyangiitis (GPA), a rare condition that causes inflammation of blood vessels. Researchers will compare the scan results with a standard clinical scoring system to see if the imaging technique can provide a more objective way to track the disease. The study involves 31 adults with newly diagnosed or relapsed active GPA.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
18F-FDG (a radioactive tracer used in PET/CT scans)
What this could lead to
If successful, this could lead to a more accurate, non-invasive way to monitor GPA disease activity, potentially improving treatment decisions.
What could go wrong
This is a small, early observational study, so results may not apply broadly. The scan's sensitivity and correlation with standard scores may be limited.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh

    Chandigarh, Chandigarh, 160012, India

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