GIANT CELL ARTERITIS
Clinical trials for GIANT CELL ARTERITIS explained in plain language.
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New IV treatment explored for painful inflammatory conditions
Disease control CompletedThis study looked at how an intravenous (IV) form of secukinumab is processed by the body and whether it is safe for adults with giant cell arteritis (GCA) or polymyalgia rheumatica (PMR). These conditions cause inflammation in blood vessels or muscles, leading to pain and stiffn…
Matched conditions: GIANT CELL ARTERITIS
Phase: PHASE1 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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New drug aims to tame blood vessel inflammation without steroids
Disease control CompletedThis study tested the drug secukinumab (Cosentyx) in 151 adults with newly diagnosed giant cell arteritis, a condition causing inflamed blood vessels. Participants were in remission and received either secukinumab or a placebo, along with a steroid taper. The goal was to see if s…
Matched conditions: GIANT CELL ARTERITIS
Phase: PHASE3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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New scan could replace needle biopsy for artery disease diagnosis
Diagnosis CompletedThis study looked at whether a PET/CT scan of the head arteries can accurately diagnose giant cell arteritis, a type of blood vessel inflammation. Researchers compared the scan results to those from ultrasound and MRI in 70 patients suspected of having the condition. The goal was…
Matched conditions: GIANT CELL ARTERITIS
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Diagnosis
Last updated Jun 27, 2026 09:00 UTC
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New digital PET/CT could spot hidden artery inflammation and prevent blindness
Diagnosis CompletedGiant cell arteritis (GCA) causes inflamed arteries and can lead to blindness if not treated quickly. This study tested a new digital PET/CT scan that can see tiny arteries in the head, which older scans missed. 92 patients with suspected GCA got both a PET/CT and an ultrasound. …
Matched conditions: GIANT CELL ARTERITIS
Sponsor: Jewish General Hospital • Aim: Diagnosis
Last updated Jun 26, 2026 13:06 UTC
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Could a tiny dose of naltrexone ease vasculitis symptoms?
Symptom relief CompletedThis study tested whether a low dose (4.5 mg) of naltrexone, a drug already used for alcoholism, can improve physical health and quality of life in people with vasculitis. Sixty participants took either the drug or a placebo daily for six weeks. The goal was to see if the drug le…
Matched conditions: GIANT CELL ARTERITIS
Phase: PHASE2 • Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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New study links common arthritis treatments to diabetes risk
Knowledge-focused CompletedThis observational study followed 198 adults aged 50–85 with giant cell arteritis or polymyalgia rheumatica to understand how common treatments (glucocorticoids and interleukin-6 inhibitors) affect diabetes risk. Researchers tracked blood sugar levels and other markers over time.…
Matched conditions: GIANT CELL ARTERITIS
Sponsor: Salome Kristensen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC