GENERALIZED ANXIETY DISORDER

This study tests an oral medication called MM120 against a placebo in 245 adults with generalized anxiety disorder. Participants take the drug or placebo for 12 weeks, and those who complete may join a 40-week follow-up where everyone gets the active drug. The goal is to see if M…

This study looks at whether adding physical exercise to cognitive behavioural therapy (CBT) helps older adults with generalized anxiety disorder more than CBT alone. About 53 participants will receive the combined treatment. The goal is to reduce worry and increase remission rate…

This phase 3 study tests whether an oral medication called MM120 can reduce anxiety symptoms in adults with generalized anxiety disorder. About 214 participants will receive either MM120 or a placebo for 12 weeks, followed by a 40-week period where everyone can receive MM120. The…

This study tests whether a group-based therapy program can help people with generalized anxiety disorder (GAD) better cope with uncertainty. About 12 to 20 adults with GAD will take part in 12 weekly online group sessions. Researchers will measure changes in anxiety, worry, and i…

This study tests a new drug called CYB004 in 36 adults with moderate to severe generalized anxiety disorder. The goal is to see if it safely reduces anxiety symptoms compared to an active control. Participants must be on a stable anxiety medication and have not responded well eno…

This study looks at whether unlicensed professionals can effectively provide cognitive behavioral therapy (CBT) to people with conditions like OCD, anxiety, depression, and PTSD. About 250 adults at Massachusetts General Hospital will receive CBT from these providers. The goal is…

This study compares two internet-based cognitive behavioral therapy programs for people with generalized anxiety disorder. About 400 adults will receive one of two 10-week online treatments targeting either intolerance of uncertainty or unhelpful beliefs about worry. Researchers …

This study compares two family-based behavioral therapies delivered via telehealth to a relaxation training program for children aged 7 to 13 with anxiety or obsessive-compulsive disorder (OCD). The goal is to see which approach works best and why, while making treatment more acc…

This study looks at whether it's possible to compare two types of cognitive-behavioral therapy (CBT) for anxiety disorders in regular psychiatric care. One approach is a general therapy that works for many anxiety types, while the other is customized for a specific disorder. The …