ESOPHAGEAL ADENOCARCINOMA
Clinical trials for ESOPHAGEAL ADENOCARCINOMA explained in plain language.
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Targeted drug combo shows promise against aggressive esophageal cancer
Disease control CompletedThis study tested whether adding the targeted drug trastuzumab to standard chemoradiation helps people with HER2-positive esophageal cancer. About 200 adults with early-stage cancer took part. The goal was to see if the combination delays cancer return or improves survival.
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 17, 2026 01:05 UTC
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New antibody drug targets Hard-to-Treat gut cancers in early trial
Disease control CompletedThis early-phase study tested a new drug called cabotamig in 33 adults with advanced gastrointestinal cancers (like colon, stomach, liver, or pancreatic cancer) that had stopped responding to standard treatments. The drug works by attaching to a marker on cancer cells and helping…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: Arbele Pty Ltd • Aim: Disease control
Last updated May 17, 2026 01:00 UTC
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Triple-Drug cocktail shows promise for tough stomach cancers
Disease control CompletedThis study tested a combination of three drugs—regorafenib, nivolumab, and chemotherapy—in 30 people with advanced or recurrent stomach, gastroesophageal junction, or esophageal cancer that could not be removed by surgery. The goal was to see if the combination was safe and effec…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Center Hospital East • Aim: Disease control
Last updated May 17, 2026 01:00 UTC
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New cancer drug SGN-B6A tested for safety in chinese patients
Symptom relief CompletedThis early-stage study tested a new drug called SGN-B6A in 6 Chinese adults with advanced solid tumors (lung, head/neck, esophageal, or stomach cancers) that had stopped responding to standard treatments. The main goal was to check the drug's safety and side effects, and to see h…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: PHASE1 • Sponsor: Seagen, a wholly owned subsidiary of Pfizer • Aim: Symptom relief
Last updated May 15, 2026 11:55 UTC
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Freeze your way to a better swallow: new hope for esophageal cancer patients
Symptom relief CompletedThis study tested a procedure called spray cryotherapy, which freezes tumors inside the esophagus, to quickly improve swallowing in 15 patients with advanced esophageal cancer. Participants received the freezing treatment during a routine scope exam, before starting chemotherapy …
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: NA • Sponsor: Hunter Holmes Mcguire Veteran Affairs Medical Center • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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Barrett's esophagus study seeks gentler treatment
Symptom relief CompletedThis study compared two common procedures for treating Barrett's esophagus, a condition that can lead to esophageal cancer. Researchers wanted to see which treatment caused less pain and discomfort for patients. 62 adults took part, and the study measured pain right after the pro…
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Phase: NA • Sponsor: Centre of Postgraduate Medical Education • Aim: Symptom relief
Last updated May 13, 2026 16:02 UTC
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Oxygen levels linked to surgical leaks in esophageal cancer patients
Knowledge-focused CompletedThis study looked at whether having low oxygen levels after surgery to remove esophageal cancer increases the chance of a leak where the esophagus is reconnected. Researchers reviewed records from over 2000 patients and compared those with low oxygen to those with normal oxygen. …
Matched conditions: ESOPHAGEAL ADENOCARCINOMA
Sponsor: Sun Yat-sen University • Aim: Knowledge-focused
Last updated May 17, 2026 01:03 UTC