Barrett's esophagus treatment showdown: which procedure hurts less?

NCT ID NCT05051475

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two endoscopic treatments for Barrett's esophagus, a condition that can lead to esophageal cancer. The goal was to see which procedure—radiofrequency ablation or hybrid argon plasma coagulation—causes less pain and is safer from the patient's viewpoint. Sixty-two adults with Barrett's esophagus took part, and researchers measured pain right after the procedure, at 7 days, and at 30 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
endoscopic radiofrequency ablation or hybrid argon plasma coagulation
What this could lead to
If one method proves more acceptable and safer, it could become the preferred treatment for Barrett's esophagus, reducing discomfort for patients.
What could go wrong
This is a small, completed study (62 people) comparing two established techniques, so it won't introduce a new treatment. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medical Centre for Postgraduate Education

    Warsaw, 02-781, Poland

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Other studies related to the condition(s) this trial covers.