DYSPNEA

This study looks at a new way to quickly figure out why someone is struggling to breathe in the emergency room. By measuring the difference between two types of carbon dioxide levels, doctors hope to tell if the cause is fluid buildup in the lungs (congestive) or something else. …

This study looks at whether a bedside ultrasound of a large vein (the inferior vena cava) can help emergency doctors quickly tell if a patient's breathing trouble is caused by fluid buildup in the lungs from heart failure or from another cause. Researchers will enroll 200 adults …

This study looks at whether using lung and heart ultrasound can help emergency doctors give the right treatment faster to older adults (over 65) who come to the ER with sudden breathing trouble. About 504 participants will be enrolled. The goal is to see if ultrasound reduces the…

This study tests whether emergency doctors using lung ultrasound in ambulances can better diagnose and treat severe shortness of breath. 40 adults with low oxygen and fast breathing will be included. Researchers will compare the treatment given before and after the ultrasound to …

This study tests whether starting a structured exercise and education program within a month of a pulmonary embolism (a blood clot in the lungs) can prevent long-term problems like poor quality of life, shortness of breath, and reduced physical ability. About 160 hospitalized pat…

This study tests whether three 15-minute hypnosis sessions can help people with persistent breathlessness from cancer, COPD, interstitial lung disease, or chronic heart failure feel more in control of their breathing. Researchers will measure changes using a standard questionnair…

This study compares two breathing techniques—segmental breathing and active cycle breathing—against standard care for people recovering from open heart surgery. Researchers want to see which method best improves oxygen levels, breathing rate, and shortness of breath. The trial wi…

This study tests whether tadalafil, a drug often used for erectile dysfunction, can reduce shortness of breath in 126 veterans who have both COPD and high blood pressure in the lungs. Participants will be randomly assigned to take either tadalafil or a placebo for six months, and…

This study tests whether a simple breathing exercise using a small handheld device can strengthen breathing muscles and reduce shortness of breath in women receiving chemotherapy for early-stage breast cancer. About 58 participants will use the device daily and be monitored for c…

This study tests a device called the Lung Master, which is meant to increase lung capacity by practicing slow, deep breaths. Twenty adults with or without breathing conditions will use the device daily at home for one month. Researchers will measure lung function before and after…

This study tests a personalized program called SPOT-ON for cancer patients suffering from severe shortness of breath. Participants will receive a combination of breathing techniques, relaxation methods, posture adjustments, and oxygen-based therapies, either starting early or aft…

This study tests whether using a hand fan can prevent or reduce shortness of breath caused by the heart drug ticagrelor. About 110 adults with acute coronary syndrome who are starting ticagrelor will be enrolled. Researchers will track how many people have breathing trouble withi…

This study looks at whether inhaling menthol can quickly relieve shortness of breath in healthy adults and people with COPD. Researchers will measure brain activity and breathing to understand how menthol works. The goal is to find a simple, drug-free way to ease breathing discom…

This study looks at 32 people who still have shortness of breath or reduced quality of life after a pulmonary embolism (a blood clot in the lungs). They will receive a special PET/CT scan before and after a pulmonary rehabilitation program to see how the treatment improves lung f…

This study aims to establish normal reference values for heart and lung function in healthy adults aged 24-68. Researchers will perform breathing tests, exercise tests, and heart ultrasounds on 200 participants without known lung or heart disease. The results will serve as a comp…

This study looks at 50 people with shortness of breath to see if a simple breathing test (oscillometry) can predict problems found during exercise testing. Participants will do both tests, and researchers will compare the results. The goal is to better understand what causes shor…

This study looks at why people with myasthenia gravis (MG) feel short of breath, even during rest or sleep. Researchers will use breathing tests, sleep studies, and questionnaires in 50 adults with MG to uncover the causes. The goal is to find better ways to ease discomfort and p…

This study uses a special type of MRI (called 129Xe gas exchange MRI) to take detailed pictures of how the lungs and heart work together. Researchers want to understand how these images change after treatments like blood transfusions or oxygen therapy. The study involves 125 adul…

This study looks at how the diaphragm, the main muscle used for breathing, works in people with lung diseases like asthma, COPD, fibrosis, and pulmonary hypertension. Researchers want to see if diaphragm problems are linked to shortness of breath. About 800 adults will take breat…