DYSLIPIDEMIA

This study tested whether a new daily pill called AZD0780 could lower 'bad' cholesterol (LDL-C) in people who already take statins. Over 400 adults with high cholesterol took different doses of the drug or a placebo for 12 weeks. Researchers measured cholesterol levels and checke…

This study tested whether a specific combination of over-the-counter food supplements could help people feel fuller and improve their cholesterol and blood sugar levels. It involved 80 overweight adults over age 45, who were split into two groups: one took the supplement mix dail…

This large, completed Phase 3 trial tested whether the drug MCI-196 could help control two common problems in people with kidney failure on dialysis: high phosphorus and high 'bad' cholesterol. The study involved 642 stable dialysis patients who were randomly assigned to receive …

This study tested whether a medication called Cipros 10 is safe and effective for treating high levels of triglycerides, a type of fat in the blood. It involved 146 adults in Brazil who had dyslipidemia but were at low-to-medium risk for heart problems. The main goal was to see h…

This study tested a lifestyle program designed specifically for Native Hawaiian and Pacific Islander communities to help control chronic health conditions like diabetes, high blood pressure, and high cholesterol. The program combined nutrition and exercise coaching with support f…

This small pilot study tested two different health coaching strategies for Black adults with obesity and related conditions like high blood pressure or prediabetes. One approach focused on weight loss, while the other focused on increasing physical activity without emphasizing we…

This was an early-stage study to check the safety of an experimental drug called ALN-APOC3 in 32 adults with dyslipidemia, which means they have unhealthy levels of fats like cholesterol and triglycerides in their blood. The main goal was to see if the drug was safe and how the b…

This early-stage study tested a new experimental drug called AZD0780 when added to existing cholesterol-lowering medications. Researchers enrolled 81 healthy adults with high 'bad' LDL cholesterol to check how the body processes the drug, its safety, and its effect on cholesterol…

This completed Phase 3 trial tested whether giving two drugs together (JW0108 and C2407) is effective and safe for people with dyslipidemia, a condition of unhealthy cholesterol levels. The main goal was to see how much the treatment lowered 'bad' LDL cholesterol. The study invol…

This study aimed to understand how fat particles called lipoproteins move through the body in healthy people and in people with high cholesterol or other blood fat disorders. Researchers tracked these particles using tiny, safe amounts of radioactive material injected into 759 pa…

This study aimed to understand how a common blood factor called lipoprotein(a) might affect the body's ability to repair blood vessels. Researchers compared blood samples from 40 adults with high and normal levels of this factor. They measured specific cells involved in vessel re…