Two cholesterol drugs better than one? new study investigates

NCT ID NCT07313124

Completed Disease control Sponsor: Beni-Suef University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed trial looked at whether taking two cholesterol-lowering drugs (rosuvastatin and ezetimibe) is more effective and safer than taking just one (rosuvastatin) for people with heart disease. 66 adults with high cholesterol were randomly assigned to one of the two treatments and followed for up to 12 weeks. The study measured changes in cholesterol levels and checked for muscle-related side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: rosuvastatin and ezetimibe
What this could lead to: If successful, this could show that a combination of two cholesterol-lowering drugs works better than one alone for heart disease patients.
What could go wrong: This is a small, completed trial with only 66 participants, so results may not apply to everyone. It also focuses on lab tests, not long-term heart outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder inherited lipid metabolism disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIOVASCULAR DISEASES (CVD)

Contacts and locations

Locations

Beni-Suef University Hospital

Banī Suwayf, Beni Suweif Governorate, 62521, Egypt

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