DOWN SYNDROME (DS)
Clinical trials for DOWN SYNDROME (DS) explained in plain language.
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New hope for down syndrome vision loss: light therapy trial launches
Disease control Recruiting nowThis Phase 3 trial tests a treatment called corneal crosslinking (CXL) for people with Down syndrome who have keratoconus, a condition where the cornea thins and bulges, blurring vision. The procedure uses vitamin B2 eye drops and ultraviolet light to strengthen the cornea. Resea…
Matched conditions: DOWN SYNDROME (DS)
Phase: PHASE3 • Sponsor: Woolfson Eye Institute • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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New chemo regimen aims to boost survival in kids with down syndrome and leukemia
Disease control Recruiting nowThis study is testing a specific set of four chemotherapy blocks in children (0-18 years) who have both acute myeloid leukemia (AML) and Down syndrome. The goal is to see if this tailored treatment can improve long-term survival and reduce harsh side effects compared to past appr…
Matched conditions: DOWN SYNDROME (DS)
Phase: PHASE3 • Sponsor: Federal Research Institute of Pediatric Hematology, Oncology and Immunology • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Can a Play-Based therapy boost development in babies with down syndrome?
Disease control Recruiting nowThis study tests a new early intervention called HEP (Homeostasis-Enrichment-Plasticity) for infants with Down syndrome, ages 4 to 12 months. The approach is child-centered and family-based, focusing on enriched environments and brain plasticity. Over 12 sessions, researchers wil…
Matched conditions: DOWN SYNDROME (DS)
Phase: NA • Sponsor: Izgi Miray Demirbag • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Hope for down syndrome: drug may stop Alzheimer's seizures
Prevention Recruiting nowThis study tests if the drug levetiracetam can prevent epileptic seizures in 120 adults over 40 with Down syndrome and Alzheimer's disease. Participants will receive either the drug or a placebo for 96 weeks. The goal is to see if the drug can stop seizures and possibly slow brai…
Matched conditions: DOWN SYNDROME (DS)
Phase: PHASE3 • Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau • Aim: Prevention
Last updated Jun 27, 2026 08:10 UTC
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Supplements may strengthen muscles in down syndrome patients
Symptom relief Recruiting nowThis study tests whether taking creatine and HMB supplements for 8 weeks can improve muscle strength, balance, and body composition in people with Down syndrome. Fifty participants will receive either the supplements or a placebo, along with nutrition education. Researchers will …
Matched conditions: DOWN SYNDROME (DS)
Phase: NA • Sponsor: Universidad de Burgos • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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Can a Home-Based program help older adults with down syndrome and their caregivers?
Knowledge-focused Recruiting nowThis study is testing whether a program delivered remotely (by video or phone) that combines exercise and dementia caregiving support is practical and helpful for older adults with Down syndrome and their caregivers. About 40 participants will take part. The goal is to see if the…
Matched conditions: DOWN SYNDROME (DS)
Phase: NA • Sponsor: University of Kansas Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC