DOWN SYNDROME (DS)
Clinical trials for DOWN SYNDROME (DS) explained in plain language.
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New drug trial aims to clear Alzheimer's-Linked brain plaques in down syndrome
Disease control Not yet recruitingThis study tests whether donanemab can safely reduce amyloid plaques in the brains of adults with Down syndrome, who are at high risk for Alzheimer's disease. Sixty participants aged 35-50 will receive either donanemab or a placebo every 4 weeks for 12 months, followed by a 12-mo…
Matched conditions: DOWN SYNDROME (DS)
Phase: PHASE4 • Sponsor: Michael Rafii, MD, PhD • Aim: Disease control
Last updated Apr 24, 2026 16:06 UTC
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Could a Vitamin-Like pill protect the brains of people with down syndrome?
Symptom relief Not yet recruitingThis early-stage study tests whether a daily pill called MIB-626 is safe for adults with Down syndrome. The goal is to see if it can help prevent or slow down Alzheimer's disease, which is common in this group. Twenty-four participants will take either the pill or a placebo for 2…
Matched conditions: DOWN SYNDROME (DS)
Phase: PHASE1 • Sponsor: Brigham and Women's Hospital • Aim: Symptom relief
Last updated May 17, 2026 05:28 UTC