DOWN SYNDROME (DS)
Clinical trials for DOWN SYNDROME (DS) explained in plain language.
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New hope to shield down syndrome minds from Alzheimer's?
Disease control Not yet recruitingThis early-stage study is testing the safety of a daily supplement called MIB-626 in adults with Down syndrome. The main goal is to see if the supplement is safe and well-tolerated, while also checking if it raises levels of a key body chemical (NAD+) linked to brain health and a…
Matched conditions: DOWN SYNDROME (DS)
Phase: PHASE1 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Building stronger bones in kids with down syndrome
Disease control Not yet recruitingThis study aims to see which type of exercise is better for improving bone strength in children with Down syndrome, who often have weaker bones. It will compare a program focused on core stability (like abdominal and back muscles) against one focused on strengthening breathing mu…
Matched conditions: DOWN SYNDROME (DS)
Phase: NA • Sponsor: Cairo University • Aim: Disease control
Last updated Mar 30, 2026 14:27 UTC
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New drug trial targets Alzheimer's risk in down syndrome
Disease control Not yet recruitingThis study is testing whether the drug donanemab can reduce the buildup of a harmful protein called amyloid in the brains of adults with Down syndrome. About 60 participants, aged 35-50, will receive monthly infusions of either donanemab or a placebo for one year, followed by an …
Matched conditions: DOWN SYNDROME (DS)
Phase: PHASE4 • Sponsor: Michael Rafii, MD, PhD • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC
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Remote fitness & support tested for down syndrome families facing Alzheimer's
Symptom relief Not yet recruitingThis study is testing a 12-week remote program to see if it's practical and helpful for adults with Down syndrome who have Alzheimer's disease and their caregivers. The program includes group exercise classes for the person with Down syndrome and weekly training and support sessi…
Matched conditions: DOWN SYNDROME (DS)
Phase: NA • Sponsor: University of Kansas Medical Center • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC