Supplements may strengthen muscles in down syndrome patients

NCT ID NCT07213063

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether taking creatine and HMB supplements for 8 weeks can improve muscle strength, balance, and body composition in people with Down syndrome. Fifty participants will receive either the supplements or a placebo, along with nutrition education. Researchers will measure changes in lean mass, handgrip strength, and bone density before and after the trial.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

creatine monohydrate and beta-hydroxy-beta-methylbutyrate (HMB) supplements

What this could lead to

If it works, this could point toward a simple supplement routine to help people with Down syndrome gain strength and improve balance.

What could go wrong

This is a small, early-stage trial with only 50 participants, so results may not apply to everyone. Supplements may not produce meaningful improvements.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SUPPLEMENTATION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Down syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Universidad de Burgos

    RECRUITING

    Burgos, Burgos, 09003, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••