DOWN SYNDROME (DS)
Clinical trials for DOWN SYNDROME (DS) explained in plain language.
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New hope for kids with down syndrome and leukemia: gentler chemo shows promise
Disease control Recruiting nowThis study tests a chemotherapy plan designed specifically for children (0-18 years) with acute myeloid leukemia (AML) and Down syndrome. The goal is to improve survival while reducing harsh side effects by using lower drug doses. About 100 children in Russia will receive four ro…
Matched conditions: DOWN SYNDROME (DS)
Phase: PHASE3 • Sponsor: Federal Research Institute of Pediatric Hematology, Oncology and Immunology • Aim: Disease control
Last updated May 17, 2026 06:22 UTC
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Supplements may strengthen muscles in down syndrome patients
Disease control Recruiting nowThis study tests whether taking creatine and HMB daily for 8 weeks can improve muscle strength, balance, and body composition in people with Down syndrome. Fifty participants will receive either the supplements or a placebo, along with nutrition advice. The goal is to see if thes…
Matched conditions: DOWN SYNDROME (DS)
Phase: NA • Sponsor: Universidad de Burgos • Aim: Disease control
Last updated May 17, 2026 06:18 UTC
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New hope for down syndrome vision loss: corneal crosslinking trial launches
Disease control Recruiting nowThis study tests an experimental eye treatment called corneal crosslinking (CXL) for people with Down syndrome who have a condition that makes the front of the eye thin and misshapen, causing blurry vision. The treatment uses vitamin B2 drops and ultraviolet light to strengthen t…
Matched conditions: DOWN SYNDROME (DS)
Phase: PHASE3 • Sponsor: Woolfson Eye Institute • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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New hope: drug may stop seizures in down syndrome Alzheimer's patients
Prevention Recruiting nowThis study tests if levetiracetam, a seizure medication, can prevent epileptic seizures in 120 adults over 40 with Down syndrome and Alzheimer's disease. Participants will receive either the drug or a placebo for 96 weeks. The goal is to see if the drug can stop seizures and poss…
Matched conditions: DOWN SYNDROME (DS)
Phase: PHASE3 • Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau • Aim: Prevention
Last updated May 17, 2026 06:21 UTC
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New HEP therapy aims to boost motor skills in down syndrome babies
Symptom relief Recruiting nowThis study tests a new therapy called HEP (Homeostasis-Enrichment-Plasticity) to help babies with Down syndrome improve their movement and sensory skills. About 26 infants aged 4 to 12 months will receive either HEP or standard therapy over 12 sessions. Researchers will measure p…
Matched conditions: DOWN SYNDROME (DS)
Phase: NA • Sponsor: Izgi Miray Demirbag • Aim: Symptom relief
Last updated May 17, 2026 06:19 UTC
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Can a remote program help older adults with down syndrome and their caregivers?
Knowledge-focused Recruiting nowThis study is testing whether a remotely delivered exercise and dementia care program is practical and helpful for older adults with Down syndrome (age 35+) and their caregivers. The goal is to see if people will join, stay in, and safely complete the 12-week program. It also loo…
Matched conditions: DOWN SYNDROME (DS)
Phase: NA • Sponsor: University of Kansas Medical Center • Aim: Knowledge-focused
Last updated May 12, 2026 13:43 UTC