CRITICAL CARE

This study looked at whether reducing the use of strong, broad-spectrum antibiotics in cancer patients with sepsis or septic shock is as safe as continuing them. The goal is to lower the risk of creating drug-resistant bacteria. Researchers compared a de-escalation strategy to st…

This study looked at whether using a device to measure pressure inside the skull helps doctors treat people with a large brain bleed. 193 patients were randomly assigned to get either standard care or care guided by the pressure monitor. The goal was to see if the monitor helped …

This pilot study tested whether a therapy that combines behavioral activation for depression with physical rehabilitation is feasible for survivors of acute respiratory failure. Fifty-two adults who had been on life support in the ICU received home visits and phone calls from the…

This study followed 400 intensive care patients receiving beta-lactam antibiotics to see how often these drugs cause brain-related side effects like confusion or agitation. Researchers measured antibiotic levels in the blood and checked patients' neurological status several times…

This completed study tested whether a package of telemedicine services — including daily rounds by a specialist, a team of nurses and therapists, and a focus on safety — could reduce how long patients stay in the intensive care unit (ICU). Researchers enrolled 22,000 patients fro…

This study tested whether a special dashboard called AWARE helps ICU doctors and nurses make decisions faster and more accurately than using standard electronic health records. 113 healthcare providers participated in a randomized trial where they answered clinical questions usin…

This study looked at whether measuring the pressure in the cuff of a breathing tube can accurately assess how hard a patient is working to breathe while on a ventilator. Researchers compared this new method to the standard, more invasive technique that uses a sensor in the esopha…

This study looked at whether a quick screening when patients leave the intensive care unit (ICU) can predict if they will have psychological issues (like depression or anxiety) or new physical disabilities three months later. Researchers followed 773 adults who stayed in the ICU …

This pilot study tested a program called PICTURE-THIS, designed to help people who survived a stay in the intensive care unit (ICU) and their families transition back home. The program includes care coordination, check-ins over three months, and rehabilitation support. The study …