CRITICAL CARE
Clinical trials for CRITICAL CARE explained in plain language.
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Brain pressure monitoring may improve outcomes after major hemorrhage
Disease control CompletedThis study looked at whether closely monitoring pressure inside the skull helps people recover from a large brain bleed. Researchers compared standard care to care guided by a pressure monitor in 193 patients. The goal was to see if this approach leads to better function and inde…
Matched conditions: CRITICAL CARE
Phase: NA • Sponsor: Xiangya Hospital of Central South University • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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Can less be more? new study tests cutting back antibiotics in cancer patients with sepsis
Disease control CompletedThis study looked at whether reducing the use of strong antibiotics in cancer patients with sepsis or septic shock is as safe as continuing them. The goal was to lower the risk of creating superbugs while still treating the infection. About 400 adult cancer patients in intensive …
Matched conditions: CRITICAL CARE
Phase: PHASE3 • Sponsor: Institut Paoli-Calmettes • Aim: Disease control
Last updated May 13, 2026 16:01 UTC
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New therapy tackles depression and physical decline after ICU stays
Symptom relief CompletedThis study tested a therapy that combines depression treatment with physical rehabilitation for people who survived respiratory failure in the ICU. The therapy was delivered via phone and home visits. The goal was to see if this approach is practical and could help improve both m…
Matched conditions: CRITICAL CARE
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated May 13, 2026 16:02 UTC
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ICU survivors: new study aims to predict hidden struggles after leaving hospital
Knowledge-focused CompletedThis observational study looked at 773 adults who stayed in the intensive care unit (ICU) for at least 12 hours. Researchers wanted to see if a screening test given when patients leave the ICU could predict if they would have psychological issues (like depression, anxiety, or PTS…
Matched conditions: CRITICAL CARE
Sponsor: Region Stockholm • Aim: Knowledge-focused
Last updated May 17, 2026 04:15 UTC
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New program aims to ease ICU recovery for patients and families
Knowledge-focused CompletedThis study tested a program called PICTURE-THIS that helps people who survived a stay in the intensive care unit (ICU) and their families transition home. The program includes care coordination and activity-based rehab delivered by a specialist team. The goal was to see if the pr…
Matched conditions: CRITICAL CARE
Phase: NA • Sponsor: University of Pittsburgh • Aim: Knowledge-focused
Last updated May 12, 2026 13:39 UTC
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Dashboard dash: new tool helps ICU doctors cut through data clutter
Knowledge-focused CompletedThis study tested whether a special information dashboard helps ICU doctors and advanced practice providers make faster and more accurate decisions compared to using their usual electronic health record system. Over 100 participants completed tasks using both methods, and researc…
Matched conditions: CRITICAL CARE
Phase: NA • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated May 11, 2026 20:48 UTC
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Breathing tube cuff may replace invasive lung monitoring
Knowledge-focused CompletedThis study looked at 30 patients on breathing machines to see if the pressure in the tube's cuff (the balloon that holds the tube in place) can show how hard they are working to breathe. Normally, doctors use a thin tube down the esophagus to measure this, which is uncomfortable.…
Matched conditions: CRITICAL CARE
Phase: NA • Sponsor: Jian-Xin Zhou • Aim: Knowledge-focused
Last updated May 04, 2026 16:20 UTC