CRITICAL CARE
Clinical trials for CRITICAL CARE explained in plain language.
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Sound waves aimed at spleen may tame deadly inflammation in septic shock
Disease control Recruiting nowThis study tests whether a non-invasive ultrasound device, aimed at the spleen, can safely reduce dangerous inflammation in people with septic shock. Septic shock is a life-threatening condition where the body's response to infection causes organ damage. Forty adults in the inten…
Matched conditions: CRITICAL CARE
Phase: NA • Sponsor: First Affiliated Hospital of Wannan Medical College • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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New ventilator strategy aims to help ICU patients breathe easier
Disease control Recruiting nowThis study tests a new method for setting ventilator support in ICU patients with acute hypoxic respiratory failure. Instead of using traditional targets like breath size and rate, the new approach adjusts support based on how hard the patient is breathing. The goal is to see if …
Matched conditions: CRITICAL CARE
Phase: NA • Sponsor: Capital Medical University • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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New therapy aims to ease grief and PTSD for families of ICU patients
Symptom relief Recruiting nowThis study tests a short therapy program called EMPOWER for family members who make decisions for critically ill patients in the ICU. The therapy includes breathing exercises, mindfulness, and coping techniques delivered by a mental health professional. Researchers will compare i…
Matched conditions: CRITICAL CARE
Phase: PHASE2 • Sponsor: Weill Medical College of Cornell University • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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ICU breathing device guidelines sought by international experts
Knowledge-focused Recruiting nowThis study brings together 30 healthcare experts from around the world to agree on the best ways to use a machine called Mechanical Insufflation-Exsufflation (MI-E) in intensive care units. MI-E helps clear mucus from the lungs, but there are no standard rules for its use in crit…
Matched conditions: CRITICAL CARE
Sponsor: Medipol University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Global ICU rehab study aims to boost recovery for ventilator patients
Knowledge-focused Recruiting nowThis study watches how different ICUs around the world help patients on breathing machines get better. It will look at what kinds of exercises and therapies are used, and how they affect recovery and quality of life. The goal is to find the best ways to help these patients recove…
Matched conditions: CRITICAL CARE
Sponsor: Universita degli Studi di Genova • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Massive study aims to decode mysteries of long ICU stays
Knowledge-focused Recruiting nowThis study looks at 7000 adult patients who stayed in the intensive care unit (ICU) for more than 5 days. The goal is to find different patterns among those who remain critically ill for a long time (over 10-14 days). By analyzing medical data, researchers hope to understand why …
Matched conditions: CRITICAL CARE
Sponsor: Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Tiny study aims to unlock mystery of ICU muscle wasting
Knowledge-focused Recruiting nowThis pilot study is looking at why some patients in the intensive care unit (ICU) develop severe muscle weakness after surgery. Researchers will take blood and small muscle samples from 20 high-risk patients to look for chemical changes that might cause or signal this weakness. T…
Matched conditions: CRITICAL CARE
Sponsor: Technical University of Munich • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Heart imaging showdown: which software is best for septic shock?
Knowledge-focused Recruiting nowThis study looks at how well two different software programs measure heart function in people with septic shock, a life-threatening infection that affects the whole body. Researchers will use existing heart ultrasound data from 60 adults to see if the measurements agree and can b…
Matched conditions: CRITICAL CARE
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC