COVID19
Clinical trials for COVID19 explained in plain language.
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Lung hormone therapy for COVID-19 ARDS trial pulled before start
Disease control TerminatedThis study aimed to see if giving a thyroid hormone (T3) directly into the lungs could help people with severe COVID-19 who needed a breathing machine. The trial was planned for adults with COVID-19 and a serious lung condition called ARDS. However, the study was withdrawn before…
Matched conditions: COVID19
Phase: PHASE2 • Sponsor: University of Minnesota • Aim: Disease control
Last updated May 17, 2026 04:15 UTC
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Baby shampoo and listerine: surprising weapons against COVID?
Disease control OngoingThis study tests whether using a 4-day routine of nasal washes with diluted baby shampoo and gargling with Listerine can lower the amount of COVID-19 virus in the nose and mouth of recently infected adults aged 18-65. Participants are randomly assigned to different wash combinati…
Matched conditions: COVID19
Phase: PHASE2, PHASE3 • Sponsor: Milton S. Hershey Medical Center • Aim: Disease control
Last updated May 17, 2026 04:12 UTC
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Could a natural compound help tame COVID-19's overactive immune response?
Disease control OngoingThis study tests whether fisetin, a natural compound that clears aging cells, can prevent hospitalized COVID-19 patients from getting worse by calming excessive inflammation. About 80 adults aged 60+ (or younger with certain health conditions) will receive fisetin or a placebo. T…
Matched conditions: COVID19
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Breathing new life: inhaled sedation may boost COVID-19 survival
Disease control OngoingThis study compares two types of sedation for COVID-19 patients with lung failure who need a breathing machine. One group gets standard intravenous (IV) sedation, while the other gets inhaled gases (volatile anesthetics) that may reduce lung swelling and improve oxygen levels. Re…
Matched conditions: COVID19
Phase: PHASE3 • Sponsor: Sunnybrook Health Sciences Centre • Aim: Disease control
Last updated May 11, 2026 20:41 UTC
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Old TB vaccine shows promise in controlling type 1 diabetes
Disease control OngoingThis study tests whether repeated doses of the BCG vaccine (originally for tuberculosis) can help adults with long-standing type 1 diabetes lower their blood sugar levels. Researchers believe BCG may improve how the body uses sugar, independent of the pancreas. The trial involves…
Matched conditions: COVID19
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 11, 2026 20:40 UTC
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COVID-19 inhaler study pulled before it started
Symptom relief TerminatedThis study was designed to see if an inhaled medication called Virazole (ribavirin) could safely help hospitalized adults with severe COVID-19 who had trouble breathing. It was a very early (Phase 1) trial that planned to enroll about 0 participants, but the study was withdrawn b…
Matched conditions: COVID19
Phase: PHASE1 • Sponsor: Bausch Health Americas, Inc. • Aim: Symptom relief
Last updated May 13, 2026 15:58 UTC
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Gut bacteria may hold key to long COVID recovery
Knowledge-focused OngoingThis study looks at how the gut microbiome might influence lingering symptoms after severe COVID-19. Researchers will measure immune markers, lung function, and gut health in 20 adults who had severe COVID within the past year. The goal is to find better ways to understand and tr…
Matched conditions: COVID19
Phase: NA • Sponsor: Medical University of Graz • Aim: Knowledge-focused
Last updated May 17, 2026 04:14 UTC
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Can tweaking online networks boost vaccine trust in underserved groups?
Knowledge-focused OngoingThis study looks at whether changing how people connect online can help improve COVID-19 vaccine attitudes and intentions, especially for African American and Latinx communities who often face health inequities. About 4,500 adults in the US with internet access are taking part. R…
Matched conditions: COVID19
Phase: NA • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated May 17, 2026 04:14 UTC
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500 COVID survivors tracked to uncover lingering health mysteries
Knowledge-focused OngoingThis study follows 500 adults who had COVID-19 to learn about long-term health issues like breathing trouble, tiredness, and lung damage. Researchers will track recovery patterns and identify who is most at risk for lasting problems. No new treatments are tested; the goal is to b…
Matched conditions: COVID19
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 04:11 UTC
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Researchers track COVID-19 rules to find what works best
Knowledge-focused OngoingThis study follows about 1,000 people in Australia to see how well they follow COVID-19 rules like quarantine and distancing. Researchers also look at the social, mental, and economic effects of these measures. The goal is to learn how to make public health responses more effecti…
Matched conditions: COVID19
Sponsor: Macfarlane Burnet Institute for Medical Research and Public Health Ltd • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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New MRI technique reveals hidden lung damage in asthma, COPD, and COVID-19
Knowledge-focused TerminatedThis study uses advanced MRI scans with special gases to see how lungs work in people with asthma, COPD, or COVID-19. Researchers will follow up to 160 patients over several years to track lung changes. The goal is to better understand why some people have severe breathing proble…
Matched conditions: COVID19
Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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Hospital Workers' antibodies tracked for a year after AstraZeneca shot
Knowledge-focused OngoingThis study looks at how well the AstraZeneca COVID-19 vaccine works in 200 hospital employees. Researchers measure antibody levels at 6 weeks, 6 months, and 12 months after vaccination to see how long protection lasts. The goal is to understand the immune response in healthcare w…
Matched conditions: COVID19
Phase: NA • Sponsor: Universitair Ziekenhuis Brussel • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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COVID-19's toll on asthma: new study aims to uncover lasting lung damage
Knowledge-focused TerminatedThis study was designed to see if COVID-19 makes asthma worse or changes how well patients can control their asthma. Researchers planned to follow two groups of asthma patients—those who had a serious COVID-19 infection and those who did not—for one year. They would measure lung …
Matched conditions: COVID19
Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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COVID-19's hidden toll on organs: diabetes connection explored
Knowledge-focused OngoingThis study looks at how COVID-19 may change organs like the heart, lungs, or kidneys in people who have diabetes and those who don't. Researchers will use scans to measure organ size and other changes in 35 adults who had COVID-19. The goal is to learn more about long-term effect…
Matched conditions: COVID19
Sponsor: AdventHealth Translational Research Institute • Aim: Knowledge-focused
Last updated May 13, 2026 15:58 UTC
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University survey reveals mixed feelings on online classes during pandemic
Knowledge-focused TerminatedThis study surveyed over 9,000 undergraduate students and teaching staff at Misr International University in Egypt to understand their satisfaction with online learning during the COVID-19 pandemic. The goal was to compare perceptions and gather feedback on the shift to virtual c…
Matched conditions: COVID19
Sponsor: Misr International University • Aim: Knowledge-focused
Last updated Apr 24, 2026 16:20 UTC
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Miniature camera peers into lungs to unlock CF mysteries
Knowledge-focused OngoingThis study tests a new, tiny camera (micro OCT) that can take detailed pictures of the airways in the lungs and nose. Researchers want to see if it works well in adults with cystic fibrosis and healthy volunteers. The goal is to better understand early lung damage, which could le…
Matched conditions: COVID19
Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Apr 24, 2026 16:07 UTC