Thyroid hormone sprayed into lungs to fight COVID ARDS? trial pulled before start
NCT ID NCT04725110
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study planned to test whether putting a thyroid hormone (T3) directly into the lungs could help people with severe COVID-19 who need a breathing machine. The goal was to reduce fluid in the lungs and shorten time on a ventilator. However, the trial was withdrawn before any patients were enrolled, so no data was collected.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
T3 (thyroid hormone) instilled directly into the lungs
What this could lead to
If it worked, this could point toward a new way to reduce lung fluid and improve breathing in severe COVID-19 patients on ventilators.
What could go wrong
The trial was withdrawn before enrolling anyone, so no results exist. The approach is experimental and unproven in humans for this condition.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Minnesota
Minneapolis, Minnesota, 55117, United States