Old TB vaccine shows promise for type 1 diabetes control

NCT ID NCT02081326

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether repeated doses of the BCG vaccine (originally for tuberculosis) can help adults with long-standing type 1 diabetes lower their blood sugar levels. About 150 participants receive either BCG or a placebo over 5 years, with follow-up for 10 years. The goal is to see if BCG can improve sugar control even when the pancreas has little function left, and also protect against infections like COVID-19.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Immunobiology Labs CNY 149

    Charlestown, Massachusetts, 02129, United States

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