Online network tweak may boost vaccine acceptance in at-risk groups

NCT ID NCT04779827

Ongoing Knowledge-focused Sponsor: University of Pennsylvania Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether changing how people interact in online social networks can improve their attitudes and intentions toward COVID-19 vaccination. Over 4,400 adults in the US with internet access will be placed into different online groups and answer health questions while seeing feedback from others. The goal is to see if less centralized and more diverse networks help reduce vaccine hesitancy and health inequities.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Online social network intervention
What this could lead to: If successful, this could show that adjusting online social networks helps reduce vaccine hesitancy and health inequities in underserved communities.
What could go wrong: This is a behavioral study, not a medical treatment. Results depend on self-reported attitudes and may not lead to actual vaccination changes or generalize beyond this online setting.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

COVID-19 heart disorder Vaccination Refusal

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COVID19 HEART DISEASES VACCINATION REFUSAL

Contacts and locations

Locations

Annenberg School for Communication

Philadelphia, Pennsylvania, 19104, United States

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