CHORDOMA
Clinical trials for CHORDOMA explained in plain language.
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Proton beam therapy targets rare skull base tumors
Disease control OngoingThis study tests whether proton beam therapy, sometimes combined with standard radiation, can control skull base chordoma—a rare tumor near the brain. Nineteen adults who had surgery to remove most of the tumor will receive this precise radiation. Researchers will track tumor rec…
Matched conditions: CHORDOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Immunotherapy duo takes on 50+ rare cancers in major trial
Disease control OngoingThis phase 2 trial tests a combination of two immunotherapy drugs (nivolumab and ipilimumab) in over 800 people with more than 50 types of rare cancers. The goal is to see if this treatment can shrink tumors by helping the immune system attack cancer cells. The study is for patie…
Matched conditions: CHORDOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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New hope for rare spine cancer: targeted therapy shows promise
Disease control OngoingThis study tests a drug called cetuximab in 29 adults with advanced or metastatic chordoma, a rare bone cancer. The goal is to see if cetuximab can shrink tumors or stop them from growing. Participants receive the drug intravenously and are monitored for response and side effects…
Matched conditions: CHORDOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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New hope for rare bone cancer: experimental drug targets advanced chordoma
Disease control OngoingThis study tests an experimental drug called BL-B01D1 in 27 adults with advanced chordoma, a rare bone cancer that has spread or cannot be removed by surgery. The main goal is to see if the drug shrinks tumors. Participants receive the drug by injection, and researchers monitor s…
Matched conditions: CHORDOMA
Phase: PHASE2 • Sponsor: Sichuan Baili Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated May 13, 2026 16:04 UTC
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Promising combo tackles rare spine tumor
Disease control OngoingThis early-stage trial tests the safety of combining an immunotherapy drug (nivolumab) with or without precise radiation (stereotactic radiosurgery) in 21 people with chordoma that has returned or spread. The goal is to see if this combination can help control the tumor with mana…
Matched conditions: CHORDOMA
Phase: PHASE1 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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New hope for kids with rare cancers: Three-Drug combo under study
Disease control OngoingThis study tests a combination of three drugs—tazemetostat, nivolumab, and ipilimumab—for children with rare tumors that lack certain proteins (INI1 or SMARCA4). The goal is to find safe doses and see if the drugs shrink tumors. About 49 children with specific cancers like atypic…
Matched conditions: CHORDOMA
Phase: PHASE1, PHASE2 • Sponsor: Susan Chi, MD • Aim: Disease control
Last updated May 13, 2026 16:00 UTC
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New hope for rare bone cancer: experimental drug ERAS-601 tested in chordoma patients
Disease control OngoingThis early-stage trial tests a new drug called ERAS-601 in 12 adults with advanced chordoma that is getting worse. The goal is to see if the drug is safe and can shrink tumors or slow the disease. Participants must have a confirmed chordoma (not a rare aggressive type) and be in …
Matched conditions: CHORDOMA
Phase: PHASE1, PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 13, 2026 16:00 UTC