CHILDHOOD OBESITY

This study tests whether a daily pill called phentermine helps teenagers aged 12 to 18 with obesity lose weight. About 240 teens will take either the drug or a placebo for 52 weeks. The main goal is to see how much their body mass index (BMI) changes, while also checking for side…

This pilot study tests a 6-month program that teaches families about healthy eating and activity, and delivers fresh fruits and vegetables to their homes. About 30 children aged 4 to 10 with obesity, along with their caregivers, will take part. The main goal is to see if the prog…

This study compares time-restricted eating (eating only within a 12-hour window each day) to standard calorie-restricted diets in 128 children aged 8-17 with obesity. Over 48 weeks, researchers will measure weight loss and how well children stick to the diet. The goal is to find …

This study tests whether adding a digital behavioral tool called Evira to standard obesity medication (liraglutide or semaglutide) helps teens with obesity lose more weight than medication alone. Forty adolescents aged 12-17 will be randomly assigned to either the combination or …

This study looks at whether text messages and a program called Building Healthy Families can help lower-income families with a child who has obesity. About 600 families will be invited through their doctor's records and then offered the program, which teaches healthy eating, phys…

This study aims to make an evidence-based childhood obesity program called COACH available to families in low-income, rural, and minority communities. About 750 children aged 6-12 with obesity and their parents will take part in a 6-month program at local community centers. The p…

This study tests a program called CHAMPION that helps children with overweight or obesity and asthma live healthier lives. The program includes doctor visits, diet advice, and health coaching. Researchers want to see if doing the program entirely online works as well as meeting i…

This study tests a digital support system called Evira for treating childhood obesity. Children weigh themselves daily at home using a special scale that sends data to an app on their parent's phone and to the clinic. The goal is to see if adding this system to standard lifestyle…

This study is testing different amounts of behavioral coaching for 900 children aged 5-17 with obesity. Kids and their caregivers are randomly assigned to receive between 13 and 26 hours of lifestyle coaching over six months, including nutrition advice, web-based learning, and co…

This study tests whether using a slower-flow bottle nipple for a few days helps babies drink less milk and develop healthier feeding patterns. Researchers will monitor 440 infants to see if the change affects how much they eat, their sucking behavior, and sleep. The goal is to fi…

This study tests whether combining a food prescription program with education on healthy feeding practices can help parents prevent chronic diseases like obesity in their children. Researchers will enroll 375 parents of children aged 4-8 in Texas. Participants will receive either…

This study tests whether playgroups or parent education classes can help toddlers develop healthy eating and activity habits. About 300 families with toddlers aged 18-36 months will be randomly assigned to one of three groups: a playgroup, a parent education class, or continuing …

This study tests whether an eHealth app that coaches parents can help lower the energy balance in children aged 2-6 who are already above the 97th BMI percentile. About 148 families will be randomly assigned to use the app or receive standard care. The goal is to see if the app c…

This study tests whether limiting when children eat to a 12-hour window each day can help prevent and manage obesity. About 1,380 fourth-grade students from different schools will take part. One group will follow the time-restricted eating plan plus receive health education, whil…

This study tests a program that combines healthy eating tips, physical activity, and WhatsApp messages to improve the health of 200 fourth-grade children in Mexico. The goal is to see if these changes can lower obesity risk and improve blood markers like cholesterol and blood sug…

This study looks at why teens with obesity often regain weight after losing it. Researchers think hormones that control appetite might be involved. Over 35 weeks, 260 teens will follow a meal replacement plan and then be monitored for weight regain. The goal is to understand the …

This study looks at how exercise and physical activity during and after pregnancy change the makeup of breast milk. Researchers want to see if these changes affect how babies use energy and grow, which could help prevent childhood obesity. The study will follow 200 mothers and th…

This study looks at children with ROHHAD syndrome, a rare condition that causes rapid weight gain and breathing problems. Researchers will take blood samples to create special cells in the lab and study their genetic activity. The goal is to understand what goes wrong in the body…

This study looks at why babies born with restricted growth (IUGR) have a higher risk of childhood obesity. Researchers will track 400 mother-infant pairs for two years, analyzing T-cell changes and DNA methylation. The goal is to uncover early biological signs that could lead to …