CERVICAL SPINAL CORD INJURY

This early-stage trial tests a brain-computer interface called BrainGate for people with paralysis from conditions like ALS or spinal cord injury. A small sensor is placed in the brain to interpret movement-related signals, allowing users to control a tablet computer just by thin…

This study is testing whether nerve transfer surgery can help people with cervical spinal cord injury regain hand function. Forty participants who have already chosen to have the surgery will be followed for two years, with regular tests of hand strength, sensation, and movement.…

This early study tests a device that reads brain signals and stimulates the spinal cord to help people with cervical spinal cord injury move their arms and hands. Three participants will have electrodes implanted in their brain and over their spinal cord. The goal is to see if th…

This early study tests a brain-computer implant that reads brain signals to help people with severe paralysis (from ALS, stroke, or spinal cord injury) communicate. The device aims to decode imagined speech and allow control of computers. Only 2 participants will be enrolled to c…

This study tests whether an implanted spinal cord stimulator can improve autonomic functions like blood pressure and heart rate in people with chronic cervical spinal cord injury. The device delivers electrical pulses to the spinal cord to help regulate involuntary body processes…

This study looks at whether nerve transfer surgery can improve arm function and quality of life in people with high-level cervical spinal cord injuries (tetraplegia). Thirty participants will receive standard nerve transfer surgery and be followed for up to 4 years. The goal is t…

This early study tests the safety and function of a brain-computer interface (BCI) implanted by a robot in people with severe paralysis. The device aims to let users control external devices like computers or phones using their thoughts. The trial enrolls 15 adults with quadriple…

Neuralink is testing a brain-computer interface called the N1 Implant, placed by a robot, to help people with severe paralysis communicate. The study will enroll 6 adults with conditions like ALS or spinal cord injury who cannot speak or use their hands well. The main goal is to …

This study tests whether a low-volume nose resistance breathing exercise using an Acapella device plus an incentive spirometer can improve lung function and reduce shortness of breath, cough, and phlegm in people with cervical spinal cord injuries. Forty-two inpatients aged 18–38…

This study tests whether a device that sends mild electrical pulses to the spinal cord can help people with a cervical (neck) spinal cord injury regain arm and hand function. The device, called the CoverEdgeX 32 Surgical Lead, is already approved for pain but is investigational f…

This study tests whether non-invasive spinal stimulation, used at home with exercise, can safely improve arm and hand function in people with recent cervical spinal cord injury. 46 participants will be randomly assigned to start the program immediately or after a 12-week delay. T…

This small early-stage study tests whether a device that combines augmented reality (AR) with functional electrical stimulation (FES) is safe and usable for people with cervical spinal cord injury. Seven participants will attend 20 one-hour sessions over 10 weeks, using the syste…

This early-phase study tests whether pairing brain stimulation with spinal cord stimulation can strengthen the signals that control hand muscles. Researchers will study healthy volunteers, people with spinal cord injury, and those with cervical myelopathy. The goal is to understa…

This study uses advanced MRI scans to look at changes in the spinal cord and fluid around it in people with spinal cord injuries. The goal is to see if these changes relate to a person's symptoms and nerve function. Researchers hope this will lead to earlier diagnosis and better …

This study explores how electrical stimulation of the spinal cord can help people with cervical spinal cord injury regain arm and hand function. Researchers will place electrodes on the spinal cord during surgery and test different stimulation patterns. The goal is to find the be…