Surgery gives new hope for hand movement after paralysis

NCT ID NCT05638191

Recruiting now Disease control Sponsor: University of British Columbia Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether nerve transfer surgery can help people with cervical spinal cord injury regain hand function. Forty participants who have already chosen to have the surgery will be followed for two years, with regular tests of hand strength, sensation, and movement. Their results will be compared to their own starting point and to similar patients who did not have surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: nerve transfer surgery
What this could lead to: If successful, this surgery could restore meaningful hand opening and closing in people with tetraplegia, improving independence and quality of life.
What could go wrong: This is a small, early-stage study with only 40 participants. Not everyone may regain useful hand function, and surgery carries risks like infection or nerve damage.

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Conditions

The condition(s) this trial relates to.

Paresis quadriplegia spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CERVICAL SPINAL CORD INJURY SCI - SPINAL CORD INJURY SPINAL CORD INJURY SPINAL CORD INJURY AT C5-C7 LEVEL TETRAPLEGIA UPPER EXTREMITY DYSFUNCTION UPPER EXTREMITY PARALYSIS UPPER EXTREMITY PARESIS

Contacts and locations

Locations

GF Strong Rehabilitation Hospital
RECRUITING

Vancouver, British Columbia, V5Z 2G9, Canada
Kingston Health Sciences Centre
RECRUITING

Kingston, Ontario, K7L 5G2, Canada
QEII Health Sciences Centre
RECRUITING

Halifax, Nova Scotia, B3H 3A7, Canada
Sunnybrook Health Sciences Centre
RECRUITING

Toronto, Ontario, M4N 3M5, Canada

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