Mind-Controlled tablets: brain implant trial aims to give voice to the paralyzed

NCT ID NCT06511934

Recruiting now Disease control Sponsor: Leigh R. Hochberg, MD, PhD. Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This early-stage trial tests a brain-computer interface called BrainGate for people with paralysis from conditions like ALS or spinal cord injury. A small sensor is placed in the brain to interpret movement-related signals, allowing users to control a tablet computer just by thinking. The main goal is to check safety over one year, with only 6 participants enrolled so far.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: BrainGate Neural Interface System (device)
What this could lead to: If successful, this could restore the ability to communicate and use tablets for people with severe paralysis, improving independence and quality of life.
What could go wrong: This is a very early, small safety trial with only 6 participants. The device requires brain surgery, and risks include infection or device failure. It may not work for everyone.

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Conditions

The condition(s) this trial relates to.

amyotrophic lateral sclerosis brain stem infarction motor neuron disorder muscular dystrophy quadriplegia spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALS BRAINSTEM STROKE CERVICAL SPINAL CORD INJURY SPINAL CORD INJURIES TETRAPLEGIA

Contacts and locations

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Locations

Masssachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States

Contact Email: •••••@•••••

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