CARPAL TUNNEL SYNDROME

This study compares a continuous cooling therapy device to traditional ice packs for pain relief after open carpal tunnel surgery. About 128 adults having the procedure will rate their pain and hand function. The goal is to see if the cooling device offers better pain control.

This study looks at whether high-intensity laser therapy (HILT) can ease pain and improve hand function in people with mild-to-moderate carpal tunnel syndrome. About 80 adults will get either real laser treatment or a sham version, plus a wrist splint. Researchers will measure pa…

This study looks at how long symptom relief lasts after a corticosteroid injection for carpal tunnel syndrome in people whose nerve tests (EMG) are normal or only mildly abnormal. Researchers will review medical records from 300 adults to see how well the injection works. The goa…

This study compares two treatments for carpal tunnel syndrome: an ultrasound-guided injection and a small-incision surgery. Researchers will measure pain and hand function in 60 adults over 12 weeks. The goal is to find which approach provides better symptom relief.

This study tests a device worn at night that gently pushes and releases on the wrist to open up space in the carpal tunnel. Researchers want to see if it reduces pain and improves hand function better than standard care. 116 adults with carpal tunnel syndrome will use the device …

This study looks at whether adding a nerve block to local anesthesia can lower pain after carpal tunnel release surgery. About 118 adults with carpal tunnel syndrome will take part. Half will get local anesthesia alone, and half will get local anesthesia plus a nerve block. Resea…

This study tests whether taking a combination of alpha-lipoic acid, vitamin E, and vitamin B can safely reduce pain, numbness, and tingling and improve hand function in people who have had carpal tunnel surgery. About 84 adults with carpal tunnel syndrome will be randomly assigne…

This study tests whether a long-acting local anesthetic called Exparel, combined with education about pain management, can help people avoid using opioids after carpal tunnel release surgery. About 64 adults with carpal tunnel syndrome will be enrolled. Half will get Exparel and …

This study tests whether a painless brain stimulation technique (tDCS plus ultrasound) can reduce chronic pain in people with carpal tunnel syndrome. About 95 adults with long-term wrist pain will receive either real or fake stimulation to see if it lowers their pain scores. The …

This study tests if combining two needle-based treatments works better than either alone for carpal tunnel syndrome. The treatments are a needle release of a wrist ligament and an injection of sugar water around the nerve. Researchers will measure pain, function, and nerve size i…

This study tests whether using a robotic arm to guide an ultrasound probe during carpal tunnel injections is better than the standard manual method. Twenty adults with moderate to severe carpal tunnel syndrome will receive a corticosteroid injection either by the robot-assisted o…

This study looks at how carpal tunnel syndrome (CTS) affects sleep quality. Researchers will use ultrasound to measure nerve changes in the wrist and compare sleep patterns between 120 CTS patients and healthy volunteers. The goal is to better understand the link between disease …

This study looks at whether a common heart procedure (using the wrist artery) can damage nerves in the hand. Researchers will check 400 people for signs of carpal tunnel syndrome and other nerve problems. The goal is to understand the risks so doctors can better inform patients.