Nerve block may ease pain after carpal tunnel release

NCT ID NCT05372393

Recruiting now Symptom relief Sponsor: Kuopio University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether adding a nerve block to local anesthesia reduces pain after carpal tunnel release surgery. 118 adults with carpal tunnel syndrome will be randomly assigned to receive either local anesthesia alone or local anesthesia plus a nerve block. Pain levels will be tracked for 72 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: local infiltration anaesthesia (lidocaine, bupivacaine, sodium bicarbonate) with or without distal median nerve block
What this could lead to: If adding a nerve block works, it could mean less pain after carpal tunnel surgery without needing stronger anesthesia.
What could go wrong: This is a small, early-stage trial (118 people) comparing two anesthesia methods. The nerve block may not reduce pain enough to be worth the extra step.

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Conditions

The condition(s) this trial relates to.

carpal tunnel syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARPAL TUNNEL SYNDROME

Contacts and locations

Locations

Kuopio University hospital, Department of Orthopaedics, Traumatology and Hand Surgery
RECRUITING

Kuopio, Northern Savonia, 70210, Finland

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