CARDIAC ARREST

This study tested whether starting ECMO (a heart-lung bypass machine) right at the location of a cardiac arrest, rather than waiting until the patient reaches the hospital, could improve survival with good brain function. Researchers enrolled 65 adults with refractory cardiac arr…

This study tested whether adding vasopressin to the standard drug epinephrine helps more people survive a cardiac arrest that happens outside the hospital. Over 2,400 adults were enrolled. The main goal was to see how many patients were alive when they reached the hospital.

This study tested whether starting a portable heart-lung machine (ECPR) right at the scene of a cardiac arrest could save more lives and protect brain function. It included 221 adults aged 18-50 with witnessed cardiac arrest that didn't respond to standard CPR. The goal was to se…

This study tested a new device called NEURESCUE in 6 adults experiencing in-hospital cardiac arrest. The device is a balloon catheter inserted through the leg artery that inflates to redirect blood flow to the heart and brain. The goal was to see if it could be deployed quickly a…

This study tested whether a special type of dialysis (high-permeability hemodialysis) could help people in shock after being revived from cardiac arrest. The idea was to filter out inflammatory substances from the blood to improve blood pressure and reduce the need for strong med…

This study tested whether a website called Heartsight could help close family members of cardiac arrest patients feel less uncertain, anxious, and burdened. Fifty-three family members were given access to the website or usual care. The goal was to see if the website was easy to u…

This study tested a mind-body program called 'Recovering Together after Cardiac Arrest' for survivors and their caregivers. 14 pairs (survivor and caregiver) took part to see if the program was feasible and helpful. The goal was to reduce emotional distress and improve well-being…

This study looked at two ways to improve CPR during cardiac arrest: changing how often rescuers switch (every 2 vs. 4 minutes) and using a device called CPRmeter that gives real-time feedback on chest compressions. Researchers measured the quality of compressions in 51 patients. …

This study looked at 130 adults who survived a cardiac arrest outside the hospital and were treated with cooling therapy. Researchers measured two simple tests—a blood protein level and a motor response score—to see if they could predict brain function 6 months later. The goal is…

This study tested if using the lower leg to push on the chest during CPR works as well as the standard hand method. About 99 paramedic and nursing students performed two minutes of chest compressions on a manikin, either with their hands or their dominant foot. The goal was to se…

This study looked at 200 adults having a cardiac arrest outside the hospital to see how long it takes paramedics to get a working IV or IO line. The goal was to find out what causes delays or failures when trying to start an IV first and then switching to an IO if needed. The res…

This study looked back at the medical records of 168 adults who survived a cardiac arrest and were treated in the intensive care unit. Researchers wanted to find early signs that could predict which patients were more likely to die within 30 days or six months. By analyzing lab r…

This study examined how the Impella heart pump changes platelet function in 30 patients with cardiogenic shock or cardiac arrest. Researchers measured markers of platelet activation and aggregation before and during pump support. The goal was to understand why some patients devel…

This study looks at how a cardiac arrest affects brain function, including memory, thinking, and emotions. Researchers will follow 48 survivors for one year, using cognitive tests and brain scans (fMRI) to track changes. Their results will be compared to a healthy control group t…

This study looked at whether giving CPR instructions over the phone before help arrives increases the number of bystanders who perform CPR. Researchers tracked 274 adults who had a cardiac arrest outside the hospital. The goal was to see if simple instructions could save more liv…

This study examined how well medical teams perform both technical skills (like chest compressions) and non-technical skills (like communication and leadership) during real cardiac arrest situations. Researchers video-recorded 36 ICU team members and used a validated tool to measu…

This study looked at 58 adults who had a cardiac arrest and were cooled to 33°C to protect their brains. Researchers compared two rewarming speeds (slow at 0.25°C per hour vs. fast at 0.50°C per hour) to see how it affected inflammation levels in the blood. The goal was to gather…

This study looked at 212 critically ill adults in one ICU to see if three blood test ratios could predict death. The ratios compare lactate, CRP, and procalcitonin to albumin levels. Researchers will check if these ratios are linked to survival and find cut-off values to help doc…

This pilot study tested whether using two defibrillators early, instead of one, is feasible and safe for people whose hearts stop outside a hospital and don't respond to the first shock. Researchers enrolled 40 adults with a shockable heart rhythm. The goal was to see if emergenc…