BURNS

This pilot study tests a new way to make a custom pressure orthosis for burn scars using 3D scanning and printing. About 25 adults with healing hypertrophic burn scars will get the device. The main goal is to see if the manufacturing process works and the orthosis fits safely.

This Phase 2 trial tests whether 4-aminopyridine, a drug already used for other conditions, can help second-degree burns heal faster. Researchers will give the drug or a placebo to 200 adults with fresh burns and track healing rate and scarring. The goal is to see if this safe, e…

This pilot study tests a device called Efferon LPS that filters the blood to remove toxins and inflammatory substances in adults with severe thermal burns. Fifteen participants will receive two filtering sessions, and their outcomes will be compared to a group of similar patients…

This study tests a device called Efferon LPS NEO that filters the blood of children with severe burns to remove harmful substances. The goal is to see if it reduces time in the ICU and improves recovery. Thirty children will receive the treatment and be compared to past cases.

This study compares two medications applied to the wound bed before placing a skin graft in people with burns. The goal is to see if a low-cost drug called tranexamic acid works as well as the standard thrombin spray to prevent blood clots under the graft. About 62 adults with sm…

This early study is testing a mineral-based spray called THERAVEX on 26 people with various wounds, including burns, pressure sores, and diabetic ulcers. The spray is used alongside standard wound care to see if it helps the skin heal better and faster. So far, it appears safe an…

This early-phase trial tests whether disposable nitrous oxide (laughing gas) canisters can reduce pain and anxiety during burn dressing changes. Thirty adult burn patients will try both the gas and a placebo in random order. The goal is to see if this offers a safer alternative t…

This study tests a special gel dressing called Plurogel against standard burn dressings in people with partial thickness burns on the face or one limb. The goal is to see if Plurogel helps burns heal faster, reduces pain, and lowers the need for skin grafts. About 25 adults will …

This pilot study tests whether a gel called PluroGel®, used with standard dressings, can help burn injuries heal better and reduce the need for skin grafting. Twenty adults with similar burns on both arms or legs will have one limb treated with the gel and the other with standard…

This study tests a new cream called MW-III on partial-thickness thermal burns (like from fire or hot liquids). It compares MW-III to a standard burn cream, Silvadene, to see which helps burns heal faster. About 60 adults with burns covering up to 25% of their body will take part.…

This study tests a telerehabilitation program that uses technology to help adults recovering from burns. Participants will do rehab exercises at home with remote guidance. The goal is to see if this approach improves joint range of motion and scar quality. The study enrolls 30 ad…

This study tests if training with a wearable robot can improve walking in people who have long-term walking problems after a severe burn injury. Twenty adults who had burns on more than half of their legs and still had trouble walking 6 months later will receive 12 weeks of robot…

This study looks at how glucose spreads in the body of adults with severe burns (covering at least 30% of their skin). Researchers will measure glucose levels after a small injection over the first four days. The goal is to see if this measurement can help guide fluid treatment i…

This registry is tracking 3,000 critically ill patients who receive the CytoSorb blood-filtering device in real-world intensive care settings. The goal is to collect data on how the device is used and whether it relates to patient survival. It covers many conditions like sepsis, …