BURNS

This study compares two medications applied to the wound bed before placing a skin graft in people with burns. The goal is to see if a low-cost drug called tranexamic acid works as well as the standard thrombin spray to prevent blood clots under the graft. About 62 adults with sm…

This study tests a device called Efferon LPS that filters the blood of adults with severe thermal burns. The goal is to see if it reduces time in the intensive care unit (ICU). Fifteen participants will receive two filtering sessions and be compared to a similar group from past r…

This study is testing a device called Efferon LPS NEO that filters the blood of children with severe thermal burns. The goal is to see if it helps them leave the intensive care unit (ICU) sooner. About 30 children will receive two blood-filtering sessions, and their recovery will…

This study tests a gel called PluroGel on burn injuries to see if it helps wounds heal better and reduces the need for skin grafts. Twenty adults with similar burns on both arms or legs will have one limb treated with PluroGel and the other with standard dressing. The goal is to …

This study tests whether a wearable robot can improve walking in people who still have trouble walking 6 months after a severe burn injury. Twenty adults will use the robot during physical therapy for 12 weeks. Researchers will measure walking speed, balance, and lung function be…

This study tests whether a handheld canister of nitrous oxide (laughing gas) can help control pain and anxiety during burn dressing changes. Thirty adults with burns covering 5-20% of their body will try both the gas and standard care to see which works better. The goal is to fin…

This study tests whether a telerehabilitation program using technology can improve recovery after a burn. About 30 adults who had a burn across a joint will use a smartphone, tablet, or computer to do rehab exercises at home. Researchers will measure changes in joint movement and…

This study tests whether a cream made from 4-aminopyridine (4-AP) can help second-degree burns heal faster and with less scarring. About 200 adults with fresh burns will receive the cream or a placebo. The goal is to see if the treatment reduces the need for skin grafts and impro…

This study tests a cream called MW-III on adults with thermal burns (up to 25% of body surface). It compares MW-III to a standard burn cream (Silvadene) to see which helps partial-thickness burns heal faster. About 60 participants will be enrolled to measure time to 95% healing a…

This study looks at how glucose (sugar) spreads in the body of adults with severe burns covering at least 30% of their skin. Researchers will measure this over the first four days in the hospital to understand fluid changes. The goal is to gather information that could help docto…

This study is a large registry that collects data on how a blood-filtering device called CytoSorb is used in real-world intensive care settings. It will include up to 3,000 critically ill patients with conditions like septic shock, severe lung injury, or liver failure. The goal i…