BREAST NEOPLASM

This study is testing whether freezing small breast tumors (cryoablation) works as well as standard surgery (lumpectomy) for early-stage breast cancer. Researchers will compare both treatments in 120 women aged 50+ with low-risk tumors to see which has fewer complications, better…

This study is testing whether proton radiation therapy can effectively control early-stage breast cancer while causing fewer side effects than traditional radiation. It focuses radiation only on the area where the tumor was removed, potentially sparing healthy breast tissue. The …

This study is testing whether a new immunotherapy combination can help people with advanced metastatic breast cancer live longer when standard treatments have stopped working. The trial will compare the experimental treatment against whatever therapy a doctor would normally choos…

This study is testing a new decision-making tool for women aged 70 and older who have a common, low-risk type of early breast cancer. The goal is to see if giving patients a detailed guide and training their surgeons in shared decision-making leads to fewer aggressive treatments …

This study is testing a new imaging method called molecular breast imaging (MBI) to see if it can better guide doctors when taking a biopsy sample from a suspicious breast lump. The goal is to improve accuracy, especially for lumps that are hard to see with standard ultrasound or…

This study is testing a new version of a tiny marker that doctors place during breast biopsies. Researchers want to see if surgeons can find and remove the new marker more easily during surgery compared to the older version. The study will also ask surgeons how satisfied they are…

This Mayo Clinic study is testing a new type of breast ultrasound to see if it can better find breast cancer and check if treatment is working. It involves 550 adult patients who either have a suspicious breast lump needing a biopsy or have been diagnosed with breast cancer and a…

This study is testing a new blood test designed to help doctors tell if a suspicious breast finding is high-risk or low-risk cancer. It uses artificial intelligence to analyze tiny particles in the blood. The goal is to see if this test can accurately classify risk and potentiall…

This study is testing whether a special exercise program can prevent nerve damage, a common and painful side effect of chemotherapy. It's for women with HER2+ breast cancer who are about to start taxane-based chemotherapy. The program combines exercise with a technique called blo…

This study is testing whether a structured, supervised exercise program helps women feel better and reduces healthcare costs while they are actively receiving treatment for breast cancer. Researchers will compare the exercise program to just giving general advice about staying ac…

This study is testing whether drinking tart cherry juice can prevent nerve pain (neuropathy) caused by a common chemotherapy drug called paclitaxel. It will enroll 86 people with breast or ovarian cancer who are starting this type of chemo. Participants will be randomly assigned …

This study aims to test a simple method for understanding the daily lives of breast cancer survivors. Researchers want to see if a 14-day mobile phone diary is a practical way to track daily stress and thinking patterns. They will recruit 30 diverse survivors who are at least fiv…