Proton beam zaps breast tumors with less damage?

NCT ID NCT01766297

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests proton radiation therapy for women with early-stage breast cancer. The goal is to see if targeting only the tumor area can keep cancer from coming back while causing fewer side effects. About 132 women aged 50 and older will take part. Researchers will track recurrence, side effects, and quality of life over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Proton radiation therapy

What this could lead to

If successful, this could offer a more precise radiation option for early breast cancer, potentially reducing side effects and improving quality of life.

What could go wrong

This is a mid-stage trial with a small number of participants. It may not show better outcomes than standard radiation, and long-term side effects are still being studied.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm ductal breast carcinoma in situ invasive ductal breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • California Protons Cancer Therapy Center

    RECRUITING

    San Diego, California, 92121, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hampton University Proton Therapy Institute

    RECRUITING

    Hampton, Virginia, 23666, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Inova Schar Cancer Institute

    RECRUITING

    Fairfax, Virginia, 22031, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Maryland Proton Treatment Center

    RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Mayo Clinic

    RECRUITING

    Scottsdale, Arizona, 85259, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • McLaren Proton Therapy Center

    RECRUITING

    Flint, Michigan, 48532, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • New York Proton Center

    RECRUITING

    New York, New York, 10035, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Northwestern Medicine Chicago Proton Center

    RECRUITING

    Warrenville, Illinois, 60555, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Oklahoma Proton Center

    RECRUITING

    Oklahoma City, Oklahoma, 73142, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact