Proton beam zaps breast tumors with less damage?

NCT ID NCT01766297

Recruiting now Disease control Sponsor: Proton Collaborative Group Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests proton radiation therapy for women with early-stage breast cancer. The goal is to see if targeting only the tumor area can keep cancer from coming back while causing fewer side effects. About 132 women aged 50 and older will take part. Researchers will track recurrence, side effects, and quality of life over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Proton radiation therapy
What this could lead to: If successful, this could offer a more precise radiation option for early breast cancer, potentially reducing side effects and improving quality of life.
What could go wrong: This is a mid-stage trial with a small number of participants. It may not show better outcomes than standard radiation, and long-term side effects are still being studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BREAST CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma breast neoplasm ductal breast carcinoma in situ invasive ductal breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER BREAST NEOPLASM BREAST TUMOR CANCER OF THE BREAST

Contacts and locations

Locations

California Protons Cancer Therapy Center
RECRUITING

San Diego, California, 92121, United States
Hampton University Proton Therapy Institute
RECRUITING

Hampton, Virginia, 23666, United States
Inova Schar Cancer Institute
RECRUITING

Fairfax, Virginia, 22031, United States
Maryland Proton Treatment Center
RECRUITING

Baltimore, Maryland, 21201, United States
Mayo Clinic
RECRUITING

Scottsdale, Arizona, 85259, United States
McLaren Proton Therapy Center
RECRUITING

Flint, Michigan, 48532, United States
New York Proton Center
RECRUITING

New York, New York, 10035, United States
Northwestern Medicine Chicago Proton Center
RECRUITING

Warrenville, Illinois, 60555, United States
Oklahoma Proton Center
RECRUITING

Oklahoma City, Oklahoma, 73142, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.